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Antithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. … Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
Categories: Immunoglobulin GProducts: GRAFALON 20 mg/ml, Grafalon 20 mg/ml Konzentrat zur Herstellung einer InfusionslösungIxekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIxekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. … As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions.
Products: TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml, COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADETPralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals.
Categories: Compounds used in a research, industrial, or household settingProducts: PAM-A INJECTION 500 mg/ampoule, CONTRATHION % 2 FLAKON, 10 ADETLevocabastine
go.drugbank.com/drugs/DB01106ApprovedLevocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Products: Levocamed 0,5 mg/ml Augentropfensuspension, Levocamed 0,5 mg/ml Nasenspray, SuspensionGlucagon
go.drugbank.com/drugs/DB00040ApprovedInvestigationalGlucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.
Products: GLUCAGEN FOR INJECTION 1 mg/ml, Gvoke HypoPen 1 mg Auto-InjectorBPC-157
go.drugbank.com/drugs/DB11882InvestigationalBepecin is under investigation in clinical trial NCT02637284 (PCO-02 - Safety and Pharmacokinetics Trial).
Synonyms: BPC-157Tenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil. … Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil].
Mixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, DESCOVY (200/10 MG)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalIt is used to treat hyperparathyroidism due to parathyroid tumours or renal failure. … Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: CINACALCET DR. REDDY'S, MIMPARA® 60 MGDimetindene
go.drugbank.com/drugs/DB08801ApprovedInvestigationalDimetindene (Fenistil) is an antihistamine/anticholinergic used orally and locally as an antipruritic.
Products: Dimestil 1 mg/g Gel, Histakut 1 mg/ml Injektionslösung