Search
Alectinib
go.drugbank.com/drugs/DB11363ApprovedInvestigationalInhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting in reduced tumour cell viability. … Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed on or were not tolerant of crizotinib, which is associated with the development of resistance
Categories: Antineoplastic and Immunomodulating AgentsProducts: ALECENSA HARD CAPSULE 150MG, Alecensa (Alectinib) Hard Capsules 150mgBasiliximab
go.drugbank.com/drugs/DB00074ApprovedInvestigationaland mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha. … A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIALDichlorobenzyl alcohol
go.drugbank.com/drugs/DB13269Approved[L1113] On the other hand, dichlorobenzyl alcohol is categorized by the FDA in the inactive ingredient for approved drug products.[L2773] … [A33047] Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical.
Mixtures: STREPSILS HONEY AND LEMON, STREPSILS SORE THROAT AND BLOCKED NOSE LOZENGEProducts: NEO BOROCILLINARosiglitazone
go.drugbank.com/drugs/DB00412ApprovedInvestigationalRosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl).
International brands: Sheng AoCategories: Alimentary Tract and Metabolism, metformin and rosiglitazoneBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigationalBy inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. … [L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018.
Categories: Antineoplastic and Immunomodulating AgentsProducts: OLUMIANT FILM-COATED TABLET 2MG, Olumiant 2mg Film-Coated TabletsSelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigational[L7117,L7120,L10145] This condition is typically treated with high dose [bortezomib] and [dexamethasone] chemotherapy followed by an autologous stem-cell transplant. … Other chemotherapies for multiple myeloma include [lenalidomide] and [dexamethasone], [thalidomide], and may include [melphalan] if the patient is not eligible for transplant.
Categories: Antineoplastic and Immunomodulating AgentsProducts: XPOVIO 20mg Film-Coated TabletCalcium acetate
go.drugbank.com/drugs/DB00258ApprovedIt has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Categories: Alimentary Tract and Metabolism, ascorbic acid (vit C) and calciumProducts: PHOS-NO 1000 MG TABLET, 180 ADETTilactase
go.drugbank.com/drugs/DB13761ApprovedInvestigational[A32591] It is considered by the WHO as part of the International Nonpropietary Names for Pharmaceutical Substances.[L2338] … It is produced as a chewable tablet that has to be taken before the consumption of a lactose-containing meal.
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismProducts: Milk Aid, Milk Aid - Tab 500mgSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalSiltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). … MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Sylvant 100mg Powder for Concentrate for Solution for Infusion, SYLVANT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIALFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalIt was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.
Categories: Metabolic Side Effects of Drugs and Substances, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: FEVARIN 100MG, Gen-fluvoxamine 100mg