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Ibrexafungerp
go.drugbank.com/drugs/DB12471ApprovedIbrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast … [A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole antifungals.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseNaphazoline
go.drugbank.com/drugs/DB06711ApprovedNaphazoline was first developed in 1942 as a nasal formulation for congestion[A176609]. … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807].
Mixtures: ALL CLEAR EYE DROPS, Visine for Allergy With AntihistamineTapinarof
go.drugbank.com/drugs/DB06083ApprovedInvestigationalTapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis.
Categories: Antipsoriatics for Topical UseTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.
Mixtures: Tim-Dor PF, Tim-Dor-LatDoravirine
go.drugbank.com/drugs/DB12301ApprovedInvestigationaltreatments available for the management of HIV-1 infection. … [L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseEfmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalIt is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It is suitable for all age groups. … It is commonly marketed as Elocta or Eloctate for intravenous injection.
Fingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigational[A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. … [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 virus.[L12654,L12657]
Categories: Experimental Unapproved Treatments for COVID-19Unexpanded umbilical cord-derived allogeneic CD34- hematopoietic stem cells
go.drugbank.com/drugs/DB28348Approvedin adult patients for whom a suitable donor is not available. … [L54116,L54106] Zemcelpro is the first approved cell therapy for blood cancer patients lacking suitable donor cells.[L54116]
Dimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigationalDimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis. … [A253917] Prior to its FDA approval, dimethyl fumarate had been used in Germany for treatment of psoriasis.[A253917]
Refractory CD22-positive B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
go.drugbank.com/conditions/DBCOND0165829Drugs: Inotuzumab ozogamicinSynonyms: Refractory CD22-positive B-cell Precursor Acute Lymphoblastic Leukemia (ALL)