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Deficiency of the interleukin-1 receptor antagonist
go.drugbank.com/conditions/DBCOND0008480Synonyms: Deficiency of interleukin-1 receptor antagonist, Interleukin-1 receptor antagonist deficiencyPovidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnimpaired wound healing, reduced wound strength, or infection in open wounds [A32988]. … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.
Mixtures: i-Drops ARTIFICIAL TEARS, SK Advanced Relief Eye DropsCategories: Compounds used in a research, industrial, or household settingHexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalOn May 28, 2010, the U.S. … Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy.
Estetrol
go.drugbank.com/drugs/DB12235ApprovedInvestigational[L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. … Estetrol is the first new estrogen introduced to the USA in over 50 years and is the first approved estetrol product in the world.
Categories: Estradiol CongenersTocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalTocopherols can be found in the diet as part of vegetable oil such as corn, soybean, sesame, and cottonseed. … The different types of tocopherol can be presented trimethylated, dimethylated or methylated in the positions 5-, 7- and 8-.
Categories: Compounds used in a research, industrial, or household settingLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedA normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.
Mixtures: Dextrose 2.5% In Half Strength Lactated Ringer's Injection, USP, (40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USPDoxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigational[L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant.[L5971] However, in 2010 it was approved for the treatment of insomnia. … [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture.
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin Receptor AntagonistsTyloxapol
go.drugbank.com/drugs/DB06439ApprovedInvestigationalTyloxapol is a non-ionic detergent often used as a surfactant.
Categories: Compounds used in a research, industrial, or household settingEstrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer
go.drugbank.com/conditions/DBCOND0111347Drugs: VepdegestrantSynonyms: Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast CancerDatopotamab deruxtecan
go.drugbank.com/drugs/DB16410ApprovedInvestigational[L52215] Datopotamab deruxtecan-dlnk (Datroway) was approved by the US FDA in January 2025 for the treatment of hormone receptor positive, HER2 negative unresectable or metastatic breast cancer. … Datopotamab deruxtecan is an antibody-drug conjugate comprising a Trop-2-directed monoclonal antibody (datopotamab) and a DNA topoisomerase-I inhibitor, DDx.
Categories: Topoisomerase I Inhibitors