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Pseudoephedrine
go.drugbank.com/drugs/DB00852Approved[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. … [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823]
Mixtures: Cold & Flu-IN-one, Cold & Flu-IN-oneTalc
go.drugbank.com/drugs/DB09511ApprovedInvestigationalIt is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. … In fact, recent studies have reported that talc increases the risk of ovarian and endometrial cancers by approximately 30 percent.
Mixtures: Face It Hd Perfect Bb Spf30 Pa 02, Face It Hd Perfect Bb Spf30 Pa 01Categories: Compounds used in a research, industrial, or household settingBordetella pertussis fimbriae 2/3 antigen
go.drugbank.com/drugs/DB10790ApprovedInvestigationalBordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct
Mixtures: Repevax Injektionssuspension in einer Fertigspritze, -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGEPotassium nitrate
go.drugbank.com/drugs/DB11090ApprovedInvestigationalIn addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. It is administered orally doses up to 30 g per animal per day [L1736]. … Potassium nitrate is a common active ingredient in toothpaste, exerting an anti-sensitivity action.
Mixtures: HyVee Inc Maximum Strength, Wal-Mart Stores Inc. EquateCategories: Compounds used in a research, industrial, or household settingCerliponase alfa
go.drugbank.com/drugs/DB13173ApprovedInvestigational[L51329] CLN2 is a predominantly pediatric-onset neurodegenerative disease caused by a deficiency in the lysosomal enzyme TPP1, leading to progressive impairment in motor and cognitive function. … [A264354, A264369] As a recombinant human TPP1, cerliponase alfa is used as an enzyme replacement therapy to restore the levels of TPP1 in patients with CLN2.[L51339]
Categories: Hydrolytic Lysosomal N-terminal Tripeptidyl PeptidaseSynonyms: Immature tripeptidyl-peptidase IPoloxamer 188
go.drugbank.com/drugs/DB11333ApprovedPoloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models [A33121]. … P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217].
Categories: Compounds used in a research, industrial, or household settingFluoroestradiol F-18
go.drugbank.com/drugs/DB15690ApprovedInvestigational[L14117] It is expected to be available in late 2020/early 2021.[L14117] … [L14096] The ability to image ER-positive tumors _in vivo_ is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression
Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin]. … Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II.
Categories: Drugs Used in DiabetesSynonyms: 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamideImlunestrant
go.drugbank.com/drugs/DB19043ApprovedInvestigationalprogression on at least one line of endocrine therapy. … [A256828] In clinical trials, imlunestrant has been investigated as monotherapy and in combination with other drugs in breast cancer patients.[A256828]
Technetium Tc-99m pertechnetate
go.drugbank.com/drugs/DB09314ApprovedInvestigationalHowever, in contrast to the iodide ion, the pertechnetate ion is released unchanged from the thyroid gland. … This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted
Categories: Compounds used in a research, industrial, or household setting