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Finasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalFinasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone … It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects.
Synonyms: (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamideMixtures: Finasteride 0.1% / Minoxidil 7%, Finasteride 0.1% / Minoxidil 5%Methyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigational[A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent.
Categories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistSynonyms: (S)-(-)-alpha-Methyldopa, α-methyl-L-dopaIbudilast
go.drugbank.com/drugs/DB05266Investigationalshrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). … Ibudilast is currently in development in the U.S. (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMethyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalAlso, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US. … A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies.
Synonyms: 17-beta-Hydroxy-17-methylandrost-4-en-3-one, 17alpha-Methyl-3-oxo-4-androsten-17beta-olCategories: 3-Oxoandrosten (4) Derivatives, Cytochrome P-450 SubstratesPiclamilast
go.drugbank.com/drugs/DB01791ExperimentalPiclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. … The structure for piclamilast was first elucidated in a 1995 European patent application and exhibits the structural functionalities of cilomilast and roflumilast.
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 4 InhibitorsSynonyms: 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide, 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-p-anisamideTozasertib
go.drugbank.com/drugs/DB19675InvestigationalTozasertib is under investigation in clinical trial NCT02532868 (A VX-680 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Cancer (0457-002)). … Tozasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor.
Categories: Heterocyclic Compounds, 1-RingPholcodine
go.drugbank.com/drugs/DB09209ApprovedIllicitPholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. … [A31742] Pholcodine is not prescribed in the United States where it is classed as a Schedule I drug. It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008.
Mixtures: Rhynacol F SyrupCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsClobetasone
go.drugbank.com/drugs/DB13158ApprovedClobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions
Categories: Corticosteroids, Moderately Potent (Group II), Cytochrome P-450 SubstratesProducts: AMISOL CREAM 0.05% w/w, CLOBUTRATE CREAM 0.05% W/WFlumequine
go.drugbank.com/drugs/DB08972ApprovedWithdrawnFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Categories: Topoisomerase II Inhibitors, 4-QuinolonesLanthanum carbonate
go.drugbank.com/drugs/DB06792ApprovedLanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals. … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects.
Synonyms: Lanthanum(3+) carbonate