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Dordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigational[A274391] Dordaviprone has several modes of action, including the activation of mitochondrial caseinolytic protease P (ClpP), antagonism of the dopamine D2 receptor,[L53833] activation of Activating Transcription
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2B6 InducersSerine
go.drugbank.com/drugs/DB00133ApprovedInvestigationalNutraceuticalA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Mixtures: Aminosyn-PF, Aminosyn-PFOleoyl-estrone
go.drugbank.com/drugs/DB04870InvestigationalBody protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show that this drug appears to avoid this effect. … It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance.
Tibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalIn June 2006, Organon Pharmaceuticals announced the receipt of a Not Approvable Letter from the U.S.
Categories: Estrogen Receptor ModulatorsTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalAs recent as 1 October 2018, the US FDA approved Antares Pharma Inc.'
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCytisine
go.drugbank.com/drugs/DB09028InvestigationalRecent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. … Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost.
G protein-coupled receptor family C group 5 member D
go.drugbank.com/bio_entities/BE0010290TargetHumansG protein-coupled receptor involved in hard keratin expression and likely plays a role in the development of hair and nails
Polypeptides: G protein-coupled receptor family C group 5 member DFunction: G protein-coupled receptor activityBismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnBismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate...
Enalapril
go.drugbank.com/drugs/DB00584ApprovedInvestigationalVet approvedEnalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte ...
Mixtures: ENALAPRIL 1A PL 20/6MG, ENALAPRIL 1A PL 20/6MGCategories: P-glycoprotein inhibitors