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Acetaminophen Metabolism Pathway
smpdb.ca/view/SMP0000640Drug metabolismAcetaminophen (APAP) is metabolized primarily in the liver. Glucuronidation is the main route, accounting for 45-55% of APAP metabolism, and is mediatied by UGT1A1, UGT1A6, UGT1A9, UGT2B15 in the liver and UGT1A10 in the gut. APAP can al...
Acetaminophen Action Pathway (New)
smpdb.ca/view/SMP0122823Drug actionAcetaminophen is an oral/IV antipyretic and analgesic drug used to treat fevers and mild to moderate pain. Its exact mechanism is unknown but it is thought to target the cyclooxygenase pathway in the CNS (brain). It does not inhibit the ...
Pheniramine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145419Drug actionPheniramine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interf...
Pheniramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174907Drug actionPheniramine is an antihistamine used to treat allergic rhinitis and pruritus. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat co...
Pheniramine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175091Drug actionPheniramine is an antihistamine used to treat allergic rhinitis and pruritus. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat co...
Acetaminophen Action Pathway
smpdb.ca/view/SMP0000710Drug actionAcetaminophen (also named paracetamol or APAP) is not a Nonsteroidal anti-inflammatory drugs (NSAIDs). However, it still can be used to treat pain and fever. Acetaminophen can block prostaglandin synthesis by the action of inhibition of ...
Drugs: Glutamic acid · Glutathione · Acetaminophen · Dinoprostone · Calcium · Magnesium cation +5 morePheniramine H1-Antihistamine Action
smpdb.ca/view/SMP0056662Drug actionPheniramine is a first-generation alkylamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such a...
Pheniramine Predicted Metabolism Pathway
smpdb.ca/view/SMP0174551MetabolicMetabolites of Pheniramine are predicted with biotransformer.