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Methylchloroisothiazolinone
go.drugbank.com/drugs/DB14197ApprovedSensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. … Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: 4-Isothiazolin-3-one, 5-chloro-2-methyl-, 5-Chloro-N-methylisothiazolin-3-oneEszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalThis sets it apart from many other hypnotic sedatives, which are generally approved only for the relief of short-term (6-8 weeks) insomnia. Eszopiclone was initially approved by the FDA in 2004. … Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate, (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine-1-carboxylateValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigational[A174124] Valsartan is generally well-tolerated with a side-effect profile superior to that of other antihypertensive drugs.[A174130,A174133] … ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis
Mixtures: CARDIK ® 3 160/5/12.5, CARDIK ® 3 160/5/12.5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsEthotoin
go.drugbank.com/drugs/DB00754ApprovedEthotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: (±)-3-ethyl-5-phenylhydantoin, 3-ethyl-5-phenylhydantoinDiflunisal
go.drugbank.com/drugs/DB00861ApprovedDiflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs.
Synonyms: 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid, 5-(2,4-difluorophenyl)salicylic acidCategories: Non COX-2 selective NSAIDSNicergoline
go.drugbank.com/drugs/DB00699ApprovedAn ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester), 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate5-deoxyflavanone
go.drugbank.com/drugs/DB03601Experimental5-deoxyflavanone is a solid. This compound belongs to the flavanones. … These are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3.
Synonyms: 5-deoxyflavanoneMethyl aminolevulinate
go.drugbank.com/drugs/DB00992ApprovedInvestigationalMethyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Synonyms: methyl 5-aminolevulinate, 5-aminolevulinic acid methyl esterProducts: METVIX® CREMA 160 MG/G, Luxerm 160 mg/g Creme5-Aminouracil
go.drugbank.com/drugs/DB03792ExperimentalCategories: Heterocyclic Compounds, 1-RingSynonyms: 5-aminopyrimidine-2,4(1H,3H)-dione, 5-Amino-2,4-dihydroxypyrimidine