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Displaying results 121 - 130 of 35175 in total
  1. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006.

    Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADETCategories: combinations of sulfonamides, Antivirals used in combination for the treatment of HIV infections
  2. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). … In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit assessment.[L46113]

    Synonyms: Caproato de hidroxiprogesteronaProducts: PROLUTON DEPOT AMPOLLAS DE 500 MG, LUGESRO 500 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET
  3. Drug

    Colfosceril palmitate

    go.drugbank.com/drugs/DB09114
    ApprovedWithdrawn

    Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. … [A31510] It was part of the first generation of commercially available artificial surfactants.[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990.

    Synonyms: Palmitate de colfosceril, Palmitato de colfoscerilo
  4. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    In contrast, low doses are found to selectively activate NE and DA neurotransmission within the prefrontal cortex which is an area of the brain thought to play a prominent role in ADHD pathophysiology, … [A177541] There is a dose-related effect of psychostimulants on receptor stimulation, where higher doses are shown to increase norepinephrine (NE) and dopamine (DA) efflux throughout the brain which can

    Categories: Medications that reduce magnesium levelsProducts: RITALINA® LA 20 MG CAPSULAS DE LIBERACION PROLONGADA, Aa-methylphenidate SR
  5. Indication

    Atrial Fibrillation or Flutter

    go.drugbank.com/conditions/DBCOND0077970
    Drugs: Digitoxin · Hydroquinidine · Quinidine
    Synonyms: AF, AF - Atrial fibrillation
  6. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Mixtures: SEFKLAV 250/62.5 MG EFERVESAN TABLET, 20 ADET, SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADETProducts: CEFACLOR RATIO 500MG KAP, CEFACLOR AL 250
  7. Drug

    Flecainide

    go.drugbank.com/drugs/DB01195
    ApprovedInvestigationalWithdrawn

    [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.

    Categories: MATE 1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: Ag-flecainide, FLECAINIDACETAT AL 50MG
  8. Drug

    Hydroxocobalamin

    go.drugbank.com/drugs/DB00200
    ApprovedInvestigational

    Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.

    Mixtures: TRIBENA APProducts: VITAMIN B12 DEP PAN 1000UG, VITAMIN B12 DEP INJ 1500UG
  9. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. … [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs).

    Mixtures: KLIOGEST FILM KAPLI TABLET, 28 ADET, TRISEQUENS FILM KAPLI TABLET, 28 ADETCategories: Sex Hormones and Modulators of the Genital System, Medications that reduce magnesium levels
  10. Drug

    Gallamine triethiodide

    go.drugbank.com/drugs/DB00483
    ApprovedWithdrawn

    A synthetic nondepolarizing blocking drug. … The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac

    Synonyms: Trietioduro de galamina, Triéthiodure de Gallamine