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Ezetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalthat NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A15202] Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous
Mixtures: TIAZOMET ® A 40/10 TABLETAS, ROTZE-BProducts: Ag-ezetimibe, EZETIMIB AL 10MGOseltamivir
go.drugbank.com/drugs/DB00198ApprovedInvestigationalOseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. … influenza is a self-limiting illness.
Products: ZYMIR-AB, Ag-oseltamivirNitrazepam
go.drugbank.com/drugs/DB01595ApprovedA benzodiazepine derivative used as an anticonvulsant and hypnotic.
Products: NITRAZEPAM AL 5, NITRAZEPAM AL 10Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. … [L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]
Products: GLIBENCLAMID AL 3.5, GLIBENCLAMID ABZ 3.5MGClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalClozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. … [L905] Due to its severe adverse effects profile, clozapine is only available through a restricted program under a Risk Evaluation Mitigation Strategy (REMS) called the Clozapine REMS Program.[L905]
Products: Aa-clozapine, CLOZAPIN ABZ 25MG TABLFolic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedFolic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted by anti-metabolite therapies such as [DB00563] as they function as DHFR inhibitors to prevent
Mixtures: Av-VITE FB, Av-VITE FBCategories: Vitamin B ComplexRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigationalRisperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. … [L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets
International brands: Risperidal M-TabProducts: Ag-risperidone, RISPERIDON AL 1MGKaolin
go.drugbank.com/drugs/DB01575ApprovedKaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. … Kaolin is a layered silicate mineral.
Mixtures: Donnagel-MB SusProducts: Look At Me Mud Face Mask Mini Pack Aloe, Look At Me Mud Face Mask Mini Pack LotusFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigationalFebuxostat is a non-purine xanthine oxidase (XO) inhibitor. … [A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular
Products: FEBUXOSTAT AL 80MG FTA, FEBUXOSTAT AL 120MG FTATamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.
Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TAMOXIFEN AL 20, TAMOXIFEN AL 30