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Displaying results 121 - 130 of 5581 in total
  1. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.

    Products: ROPINIROL - CT 2MG RET TAB, REQUIP MODUTAB 2MG RET
  2. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    [F4645] It is also used off-label for the management of chorea associated with Huntington's disease and for the treatment of intractable hiccups as it is a potent antiemetic. … [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A27477] it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor

    Products: HALDOL JANSSEN 10MG, Haloperidol-10 Tab 10mg
  3. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases cha...

    Products: OMEPRADEX EC TABLET 20mg, OMEPRAZOL RATIO NT 10MG HK
  4. Drug

    Dicyclomine

    go.drugbank.com/drugs/DB00804
    ApprovedInvestigational

    [A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable.

    Products: Protylol Tab 20mg, Bentylol Tablet 20mg
  5. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56092, A257419] Unlike folic acid, leucovorin does not require the enzyme dihydrofolate reductase (DHFR) for activation, allowing it to function even when DHFR is inhibited by drugs like methotrexate … [A275451] It is primarily indicated for "leucovorin rescue" to diminish the hematologic and mucosal toxicity of high-dose methotrexate therapy in osteosarcoma and to treat inadvertent overdoses of folic

    Products: BENDAFOLIN 10MG/ML 200MG, LEUCOVORIN 10MG/ML 30MG
  6. Drug

    Succinylcholine

    go.drugbank.com/drugs/DB00202
    ApprovedInvestigational

    [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures.

    Products: Anectine Inj 20mg/ml, Quelicin Inj 20mg/ml USP
  7. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.

    Mixtures: OPSYNVI (10mg macitentan/ 20mg tadalafil) film-coated tablets, OPSYNVI (10mg macitentan/ 40mg tadalafil) film-coated tabletsProducts: TADACIP 10MG, DURAX FAST VSD 10MG
  8. Drug

    Manidipine

    go.drugbank.com/drugs/DB09238
    ApprovedInvestigationalWithdrawn

    It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.

    Mixtures: VIVACE 30/10MG TABLETTEN, VIVACE 30/10MG TABLETTENProducts: MANYPER 10MG, MANYPER 20MG
  9. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. … It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring.

    Mixtures: ACETAMINOFEN 325 MG + N-BUTILBROMURO DE HIOSCINA 10MG TABLETAS, ACETAMINOFEN 325 MG + N-BUTILBROMURO DE HIOSCINA 10MG TABLETASProducts: Uscine Tablets 10mg, Buscopan Sup 10mg
  10. Drug

    Bismuth subgallate

    go.drugbank.com/drugs/DB13909
    Approved

    internal deodorant where it is often employed as the primary active ingredient. … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed.

    Products: Devrom Chew Tab 200mg