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Imipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalTertiary amine TCAs, such as imipramine and amitriptyline, are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and desipramine. … Imipramine has less sedative and anticholinergic effects than the tertiary amine TCAs, amitriptyline and clomipramine.
Products: PMS Imipramine Tab 10mg, Tofranil 10mgLoxapine
go.drugbank.com/drugs/DB00408ApprovedInvestigationalAn antipsychotic agent used in schizophrenia. [PubChem]
Products: Loxapac Tab 10mg, Loxapac - Tab 10mgLercanidipine
go.drugbank.com/drugs/DB00528ApprovedInvestigationalWithdrawnIt is sold under various commercial names including Zanidip.
Mixtures: ZANIPRESS 20MG/10MG, ZANIPRESS 20MG/10MGProducts: CARMEN 10MG, LERCANIDIPIN PUREN 10MGMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalIt received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. … [A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the same indication.[L44106,L47471]
Products: CAMZYOS® 10MG CAPSULAS DURAS, KOPOZGO 10mg capsulesLenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigational[A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. … [A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal
Products: CIFEROL® 10MG, LENLI CAPSULES 10MGChlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitIt has also been used in the symptomatic treatment of alcohol withdrawal.
Products: Corax Cap 10mg, Novo-poxide 10mgIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Products: ISOFACE 40MG, ISODERM 10MGCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigational[A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell … Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes.
Products: MAVENCLAD TABLET 10MG, Mavenclad 10mg TabletsAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalIt is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.
Mixtures: Osmolex ER, Osmolex ERProducts: Symmetrel Syrup 10mg/ml, PHL-amantadine Syrup 10mg/mlCisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Products: Prepulsid Tab 10mg, CISAPRIDA TABLETAS 10MG