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Displaying results 121 - 130 of 10000 in total
  1. Drug

    Hypochlorite

    go.drugbank.com/drugs/DB11123
    ApprovedInvestigational

    Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. … Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    MAK-683

    go.drugbank.com/drugs/DB19205
    Investigational

    Synonyms: 1,2,4-TRIAZOLO(4,3-C)PYRIMIDIN-5-AMINE, N-((5-FLUORO-2,3-DIHYDRO-4-BENZOFURANYL)METHYL)-8-(2-METHYL-3-PYRIDINYL)-, N-((5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)(1,2,4)triazolo(4,3-c)pyrimidin-5-amine
  3. Drug

    ABX-MA1

    go.drugbank.com/drugs/DB33712
    Experimental

    Synonyms: ABX-MA1
  4. Drug

    Ezetimibe

    go.drugbank.com/drugs/DB00973
    ApprovedInvestigational

    that NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A15202] Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous

    Mixtures: TIAZOMET S®, TIAZOMET S®Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2C8 Inhibitors
  5. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].

    Mixtures: NIF-TEN CAPSULE, NIF TEN 50Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
  6. Drug

    Afatinib

    go.drugbank.com/drugs/DB08916
    ApprovedInvestigational

    by an FDA-approved test [L2939]. … Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Mar-afatinib, GIOTRIF® 30 MG
  7. Drug

    Dapsone

    go.drugbank.com/drugs/DB00250
    ApprovedInvestigational

    A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

    Mixtures: Dapsone 6% / Niacinamide 4%, Dapsone 6% / Niacinamide 2% / Spironolactone 5%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inducers
  8. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism

    Mixtures: Vitamine Du Groupe B Plus Fer - Liq, Multivit Et Fer Ampoules Et ComprimesCategories: Vitamin B Complex, Vitamin D and Analogues
  9. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. … This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 transcription.

    Mixtures: Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1%, Niacinamide 4% / Tacrolimus 0.1%Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  10. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. … Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone.

    Mixtures: HC Max Hongo Cura, HC Max Hongo CuraProducts: HC Max Hongo Cura MS, Dr. Luke Nail Repair Pen