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Displaying results 1301 - 1310 of 5504 in total

Drug
Lasmiditan
go.drugbank.com/drugs/DB11732
ApprovedInvestigational
[A187316] Triptans abort migraines via action at several serotonin receptors, including 5-HT1D and 5-HT1B receptors, and activity at the 5-HT1B receptor has been specifically … [L9338,L9356] It was also approved by the European Commission on August 17, 2022.[L43997] Traditionally, the triptan class of anti-migraine medications (e.g.
Categories: Serotonin (5-HT) 1F Receptor Agonists
Drug
Triamterene
go.drugbank.com/drugs/DB00384
Approved
[A177985] Since it acts on the distal nephron where only a small fraction of sodium ion reabsorption occurs, triamterene is reported to have limited diuretic efficacy. … It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side.
Mixtures: TRIAMETERENO E HIDROCLOROTIAZIDA CAPSULAS, Riva-zide 50/25mg Tablets
Drug
Aprotinin
go.drugbank.com/drugs/DB06692
ApprovedInvestigationalWithdrawn
For this use, it is typically administered by injection. … Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and liver surgery.
Mixtures: ŞTİ.EL LYO 1 ML TROMBIN ÇÖZELTİSİ VE 1 ML FIBRINOJEN ÇÖZELTİSİ ICEREN IKI BILESENLI FIBRIN YAPISTIRICI, SET 1 (2 İĞNE+2 ENJEKTÖR) VE SET 2 (2 İĞNE +2 ENJEKTÖR+1 ENJEKTÖR KLİPSİ+2 BİRLEŞTİRME PARÇASI+ 4, BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI
Drug
Clavulanic acid
go.drugbank.com/drugs/DB00766
ApprovedInvestigationalVet approved
[A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav, or Clavulin.[L7880,L7904,L7910]
Mixtures: SUMIVULIN ® 600 (500MG/100MG), BİOMENT-BID 200MG/28MG ORAL SÜSPANSİYON İÇİN KURU TOZ
Drug
Iloperidone
go.drugbank.com/drugs/DB04946
ApprovedInvestigational
[A3024] It is considered to be a second-generation antipsychotic drug [A263552] with multiple receptor binding profile, although it shows high affinity towards 5-HT2A and dopamine D2 receptors
Drug
Heparin
go.drugbank.com/drugs/DB01109
ApprovedInvestigational
It is a naturally occurring anticoagulant released from mast cells. … It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa.
Drug
Tagraxofusp
go.drugbank.com/drugs/DB14731
ApprovedInvestigational
It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_. … [A253762] It was also approved by the European Commission on January 7, 2021.[L43712]
Drug
Pramocaine
go.drugbank.com/drugs/DB09345
Approved
It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation. … It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders
Mixtures: Analpram E, Analpram ECategories: Antihistamines, Anesthetics, Etc.
Drug
Ammonia
go.drugbank.com/drugs/DB11118
ApprovedInvestigational
It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. … It is present in normally present in all tissues constituting a metabolic pool, where it is mostly taken up by glutamic acid and take part in transamination and other reactions, including the synthesis
Mixtures: Physician EZ Use Joint Tunnel and Trigger Kit, Physician EZ Use Joint Tunnel and Trigger Kit
Drug
Tinzaparin
go.drugbank.com/drugs/DB06822
ApprovedInvestigational
It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. … LMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.