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Safflower oil
go.drugbank.com/drugs/DB09446ApprovedInvestigationalWithdrawnGamma linolenic acid (GLA) safflower oil is marketed as an over-the-counter dietary supplement.
Papain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnPresent in over-the-counter mixture products consisting of different digestive enzymes, its active site contains a catalytic diad that plays a role in breaking peptide bonds.
Phenazopyridine
go.drugbank.com/drugs/DB01438ApprovedInvestigationalPhenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug ...
ETC-588
go.drugbank.com/drugs/DB05456ExperimentalETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in removing accumulated cholesterol and other lipids from cells ...
Vintafolide
go.drugbank.com/drugs/DB05168InvestigationalVintafolide is a folate-targeted chemotherapeutic conjugate (folate vitamin + vinca alkaloid) in clinical stage development as a treatment for folate-receptor positive cancers.
Fenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnFenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and liste...
Durvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigationalDurvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durval...
Alprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigationalAlprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole. Benzodiazepine trea...
Macadamia seed oil glycereth-8 esters
go.drugbank.com/drugs/DB14318InvestigationalMacadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Decitabine
go.drugbank.com/drugs/DB01262ApprovedInvestigationalMyelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of ...