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Inclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigationalBy binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. … [L28178] Inclisiran was later approved by the FDA on December 22, 2021, for the treatment of heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease in adults
Products: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, LYPTİMZİA 284 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETRozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigational[L47122] This is due to the efficacy demonstrated in the pivotal Phase 3 MycarinG study (NCT03971422).[L47122] Rozanolixizumab was also approved by the European Commission on January 5, 2024.[L50973] … [A260187,A260192,A260197] Approximately 80% of myasthenia gravis patients tested positive for the AChR autoantibodies, and 40% of these AChR-negative or seronegative patients were found to have MuSK autoantibodies
Products: Rystiggo 280 mg/2 ml Enjeksiyonluk Çözelti, 1 adetTetryzoline
go.drugbank.com/drugs/DB06764Approved[L32579] Tetryzoline is also found in combination products with other lubricants and anti-irritants, such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate].
Mixtures: EFEMOLINE 5 ML DAMLA, FLU-SURE T® SUSPENSIÓN OFTÁLMICAProducts: RHİNOSİDE DAMLA, 10 ML, VISINE 0,5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 5 MLMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: Selutrio 10, Aminosyn II 7% M In 10% Dextrose(dual Chamber)Products: Slow-mag, Slow-mag-tabMaribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigational[L39322] Most standard CMV therapies, such as [ganciclovir] or [foscarnet], target CMV DNA polymerase - while generally effective, these medications tend to promote the development of CMV resistance to … Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Livtencity 200 mg Film Kaplı Tablet (56 Adet), Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet)Felbamate
go.drugbank.com/drugs/DB00949ApprovedIn particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). … Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak inhibitory effect on GABA receptor binding sites.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: Taloxa 600 mg/5 ml - orale Suspension, Taloxa 600 mg TablettenFestuca pratensis pollen
go.drugbank.com/drugs/DB10370ApprovedFestuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.
Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesProducts: Standardized Grass Pollen - Meadow Fescue (100 Bau/ml), Standardized Grass Pollen - Meadow Fescue (1000 Bau/ml)Cefoperazone
go.drugbank.com/drugs/DB01329ApprovedInvestigationalWithdrawnCefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against <i>Pseudomonas</i> infections. … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis
Mixtures: PRİMASEF 500 MG IM/IV ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET, PRİMASEF 1000 MG IM/IV ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADETSynonyms: (6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure, (6R,7R)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidTrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalTrandolapril may be used to treat mild to moderate hypertension, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, as an adjunct treatment … It is metabolized to its biologically active diacid form, trandolaprilat, in the liver.
Mixtures: VERACOMB MR 180/2 MG KAPSÜL, 28 ADET, VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADETProducts: GOPTEN 0,5 MG SERT KAPSUL, 20 ADET, GOPTEN 2 MG KAPSUL, 28 ADETIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigational[L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. … Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).
Categories: Immunoglobulin G, Increased T Lymphocyte ActivationProducts: YERVOY 5 mg/ml concentrate for solution for infusion, YERVOY®5 MG /ML SOLUCION INYECTABLE PARA INFUSION INTRAVENOSA