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Displaying results 1311 - 1320 of 8468 in total
  1. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. … [L43917] As of November 2022, it is the primary circulating variant of concern according to the World Health Organization.

  2. Drug

    Ethynodiol diacetate

    go.drugbank.com/drugs/DB00823
    Approved

    that has never been marketed, see [DB13866]). … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive.

  3. Drug

    Buclizine

    go.drugbank.com/drugs/DB00354
    Approved

    [L6217] Following this, it was touted to be effective as an appetite stimulant in children when administered in the syrup form, however, this indication has not been validated. … It was manufactured by Stuart Pharms and initially approved by the FDA in 1957.

  4. Drug

    Birch bark extract

    go.drugbank.com/drugs/DB16536
    ApprovedInvestigational

    (white birch), although hybrids of both species are used as well. … [L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023.

  5. Drug

    Benralizumab

    go.drugbank.com/drugs/DB12023
    ApprovedInvestigational

    [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction. … [A31293] Benralizumab was FDA approved on November 14, 2017, and was developed by MedImmune, AstraZeneca's global biologic research and development arm.[L1019]

  6. Drug

    Etofamide

    go.drugbank.com/drugs/DB13258
    Approved

    Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued [L5617].

  7. Drug

    Phenprocoumon

    go.drugbank.com/drugs/DB00946
    ApprovedInvestigationalWithdrawn

    Coumarin derivative that acts as a long-acting oral anticoagulant.

  8. Target

    Protective antigen

    go.drugbank.com/bio_entities/BE0004747
    TargetBacillus anthracis

    PA induces immunity to infection with anthrax (PubMed:11544370). … PA associated with LF forms the lethal toxin (LeTx) and causes death when injected; PA associated with EF forms the edema toxin (EdTx) and produces edema (PubMed:1651334).

    Synonyms: PA, pag
  9. Drug

    Methysergide

    go.drugbank.com/drugs/DB00247
    ApprovedWithdrawn

    It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids.

  10. Drug

    Prednicarbate

    go.drugbank.com/drugs/DB01130
    Approved

    It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. … Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as [hydrocortisone].