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Leniolisib
go.drugbank.com/drugs/DB16217ApprovedInvestigationalLeniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a ...
Synonyms: Cdz-173 free base, Cdz173 free baseCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesCarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigational[T394] The first approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and approved on 2014. … An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.
Mixtures: ANTIPAR 200 MG/50 MG/200 MG FILM KAPLI TABLET, 100 ADET, ANTIPAR 50 MG/ 12,5 MG/ 200 MG FİLM KAPLI TABLET, 100 ADETProducts: Carbidopa Tablets, 25 mgEprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation oc...
Mixtures: TEVETEN PLUS 600 MG/12.5 MG FİLM KAPLI TABLET, 56 ADET, Teveten Plus 600 mg/12,5 mg FilmtablettenSynonyms: (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid, (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acidIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalIdebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). … It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and consequently protects
Mixtures: EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLET, EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLETSynonyms: 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone, 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinoneLeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigational[A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the tradename Lupron™ by Abbvie Endocrine Inc. … [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing downstream modulation of both gonadotropin hormone and sex steroid levels.
Products: LUCRIN INJECTION 5 mg/ml, LUPRON 5 MG/ML INYECTABLETocofersolan
go.drugbank.com/drugs/DB11635ApprovedD-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis [L2371]. … In addition to the above, tocofersolan has been studied as a promising application as an absorption enhancer in drug delivery [MSDS].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: -TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE, -TOCOPHEROL POLYETHYLENE GLYCOL 1000 SUCCINATEOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigationalin MS therapy. … [A189336] In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ZEPOSİA 0,92 MG SERT KAPSÜL, 28 ADETIdursulfase
go.drugbank.com/drugs/DB01271ApprovedInvestigationalIdursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal idur...
Products: ELAPRASE 2 MG/ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, Elaprase (TM) Solution for Intravenous Infusion 2mg/ mlEribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439].
Products: HALAVEN 0.5 mg/ml solution for injection, Eribulin Advanz Pharma 0,44 mg/ml InjektionslösungScopolamine
go.drugbank.com/drugs/DB00747ApprovedInvestigational[A228758, L31578] Due to its dose-dependent adverse effects, scopolamine was the first drug to be offered commercially as a transdermal delivery system, Scopoderm TTS®, in 1981. … [A228773, L31578] Scopolamine was first approved by the FDA on December 31, 1979, and is currently available as both oral tablets and a transdermal delivery system.[L31578]
Mixtures: Me-PB-Hyos, Me-PB-HyosCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates