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Pegaspargase
go.drugbank.com/drugs/DB00059ApprovedInvestigationalIn humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia cells have low levels of this enzyme and depend on exogenous sources. … Therefore, the use of pegaspargase results in leukemic cell death.
Categories: Compounds used in a research, industrial, or household settingFlibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalFlibanserin's mechanism of action is attributed to its high affinity for 5-HTA1 and 5-HTA2 receptors, displaying agonist activity on 5-HTA1 and antagonist on 5-HTA2, resulting in lowering of serotonin … In December of 2025 the FDA expanded the age of the indication to include postmenopausal women, a first for the FDA and sexual health in that age group. [L54893]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeGlutamic acid
go.drugbank.com/drugs/DB00142ApprovedInvestigationalNutraceuticalA peptide that is a homopolymer of glutamic acid.
Mixtures: Glutamic Acid Hydrochloride Nu Life, PEPZAN 225 MG/225 MG FİLM TABLET, 20 ADETNitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natri...
Mixtures: Baroprine 10 mg/20 mg Tabletten, Cenipres 10 mg/20 mg TablettenProducts: CONETRIN 20 MG, CONETRIN 10 MGMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: OQ-BALANS, OQ-BALANSSpiramycin
go.drugbank.com/drugs/DB06145ApprovedInvestigationalWithdrawnSpiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of … Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in oral formulations since 1955, and parenteral formulations since 1987.
Mixtures: METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADET, METİRASİN 1,5 MIU/250 MG FİLM KAPLI TABLET, 10 ADETTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalIn dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Mixtures: EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADET, EMEDUR 200 MG SUPOZITUAR, 100 ADETProducts: VOMITIN 100 MG 6 AMPUL, VOMITIN 200 MG 6 AMPULDexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawnDexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.
Categories: Compounds used in a research, industrial, or household settingProducts: Cyrdanax 20 mg/ml Pulver zur Herstellung einer InfusionslösungAducanumab
go.drugbank.com/drugs/DB12274ApprovedInvestigationalof Alzheimer's disease. … [A235668] Based on Mini-Mental State Examination and Clinical Dementia Rating (CDR), patients taking aducanumab showed signs of slowing progression; however, these data were controversial.
Ferumoxytol
go.drugbank.com/drugs/DB06215ApprovedInvestigational[L54501] The drug remains approved in the US, with a new indication being approved in October of 2025 for Ferumoxytol's use as a diagnostic agent for MRI of the brain. … In January of 2015, the EMA withdrew marketing authorisation for Rienso (ferumoxytol) due to safety concerns.
Categories: Compounds used in a research, industrial, or household setting