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Displaying results 1321 - 1330 of 10000 in total
  1. Target

    Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

    go.drugbank.com/bio_entities/BE0002195
    TargetEnzymeHumans

    Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:25419660). … Essential for normal biosynthesis and secretion of type IV collagens (Probable) (PubMed:18834968). Essential for normal formation of basement membranes (By similarity)

    Polypeptides: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
  2. Target

    Disintegrin and metalloproteinase domain-containing protein 9

    go.drugbank.com/bio_entities/BE0003412
    TargetHumans

    Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. … May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins

    Polypeptides: Disintegrin and metalloproteinase domain-containing protein 9
  3. Target

    Sodium- and chloride-dependent GABA transporter 3

    go.drugbank.com/bio_entities/BE0004733
    TargetHumans

    Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity) … Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).

    Polypeptides: Sodium- and chloride-dependent GABA transporter 3
  4. Target

    Disintegrin and metalloproteinase domain-containing protein 33

    go.drugbank.com/bio_entities/BE0019245
    TargetHumans

    Metalloprotease that cleaves and sheds the ectodomains of cell-surface proteins and thereby contributes to angiogenesis, cell differentiation, inflammation, and cell proliferation (PubMed:14676211, PubMed … Promotes and maintains a proliferative phenotype in vascular smooth muscle cells through regulation of the PI3K/AKT and ERK signaling pathways (PubMed:33982767).

    Polypeptides: Disintegrin and metalloproteinase domain-containing protein 33
  5. Drug

    Ethosuximide

    go.drugbank.com/drugs/DB00593
    ApprovedInvestigational

    An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.

    Products: Petinimid 250mg - Kapseln
  6. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. … Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

    Categories: Antineoplastic and Immunomodulating AgentsSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
  7. Drug

    Xanthinol

    go.drugbank.com/drugs/DB09092
    ApprovedWithdrawn

    [L1079] Xaninthol is known to be a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose metabolism resulting in an increased energy … [L1080] It was approved as a drug in 1998 in Canada and nowadays its status is cancelled post marketing.

    Products: Complamin Tab 150mg
  8. Drug

    Quinidine

    go.drugbank.com/drugs/DB00908
    Approved

    [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. … A phenomenon known as “quinidine syncope” was first described in the 1950s, characterized by syncopal attacks and ventricular fibrillation in patients treated with this drug.

    Mixtures: Dextromethorphan hydrobromide and quinidine sulfate, Dextromethorphan Hydrobromide and Quinidine SulphateCategories: Quinine and stereoisomer, Metabolic Side Effects of Drugs and Substances
  9. Drug

    Silver

    go.drugbank.com/drugs/DB12965
    ApprovedInvestigational

    Silver nanoparticles especially have been widely used in industrial, household, and healthcare-related products due to their potent antimicrobial activity. … Having critical roles in various applications inducing chemical and industrial fields, silver compounds have also been used in the field of medicine for centuries due to their broad-spectrum biological

    Mixtures: Silver Ion Rinse-free Hand Sanitizing Gel, iBrea Micro Silver Hand with Pure SilverCategories: Antiseptics and Disinfectants
  10. Drug

    Lycopene

    go.drugbank.com/drugs/DB11231
    Approved

    Lycopene is a non-essential human nutrient that is classified as a non-provitamin A carotenoid pigment since it lacks a terminal beta-ionone ring [A27242] and does not mediate vitamin A activity. … Lycopene is a naturally occurring red carotenoid pigment that is responsible for red to pink colors seen in tomatoes, pink grapefruit, and other foods [A27242].

    Mixtures: Shine CO-Q PlusProducts: GNC Lycopene 15mg