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Displaying results 1321 - 1330 of 10000 in total
  1. Drug

    Dirocaftor

    go.drugbank.com/drugs/DB16143
    Investigational

    Dirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis).

  2. Drug

    Furaprevir

    go.drugbank.com/drugs/DB12785
    Investigational

    Furaprevir is under investigation in clinical trial NCT01523990 (A Study to Evaluate the Safety, Tolerability, and PK in Healthy Volunteers and HCV Genotype 1 Infected Patients).

  3. Drug

    Evolocumab

    go.drugbank.com/drugs/DB09303
    ApprovedInvestigational

    It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line therapies. … Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen.

  4. Drug

    Ifosfamide

    go.drugbank.com/drugs/DB01181
    ApprovedInvestigational

    Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.

    Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: IFOSFAMIDA 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE., HOLOXAN 1 G IV İNFÜZYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET
  5. Drug

    Lotiglipron

    go.drugbank.com/drugs/DB21631
    Investigational

    Lotiglipron is under investigation in clinical trial NCT05579977 (Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People … Lotiglipron has a monoisotopic molecular weight of 574.2 Da.

  6. Drug

    Chlorpromazine

    go.drugbank.com/drugs/DB00477
    ApprovedInvestigationalVet approved

    Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  7. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  8. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    Product which allowed it to have a status a priority review. … [A39990] Rifamycin has had several direct derivative products such as rifamycin SV, rifaximin, rifampin and rifamycin CV.

    Synonyms: Rifamicine SV, Rifamycin SVCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  9. Drug

    Suramin

    go.drugbank.com/drugs/DB04786
    Investigational

    A polyanionic compound with an unknown mechanism of action. … Suramin is manufactured by Bayer in Germany as Germanin®.

  10. Drug

    Bromothalonil

    go.drugbank.com/drugs/DB14199
    Approved

    Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. … Sensitivity to Bromothalonil may be identified with a clinical patch test.

    Categories: Compounds used in a research, industrial, or household setting