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Nicorandil
go.drugbank.com/drugs/DB09220ApprovedInvestigationalWithdrawnIt is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels. … Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan.
Categories: Vasodilators Used in Cardiac DiseasesSynonyms: N-(2-Hydroxyethyl)nicotinamide nitrate, N-(2-Hydroxyethyl)nicotinamide nitrate (ester)Ioxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnThis drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. … Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast agents [L1883].
Categories: Compounds used in a research, industrial, or household settingDapagliflozin
go.drugbank.com/drugs/DB06292ApprovedInvestigationalDapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. … [A261601] Dapagliflozin was originally approved by the FDA on Jan 08, 2014, to improve glycemic control in adults with type 2 diabetes in conjunction with diet and exercise.
Categories: Drugs Used in DiabetesSemaglutide
go.drugbank.com/drugs/DB13928ApprovedInvestigational[L41335] On May 31, 2023, the FDA issued a warning regarding the use of compounded semaglutide after receiving adverse event reports. … [L8678] The subcutaneous injection is administered once weekly and the tablet is administered once a day.
Categories: Drugs Used in DiabetesProducts: OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML, OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/MLGadofosveset trisodium
go.drugbank.com/drugs/DB06705ApprovedGadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. … In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels.
Categories: Compounds used in a research, industrial, or household settingMolsidomine
go.drugbank.com/drugs/DB09282ApprovedWithdrawnInterestingly, it is being studied as being a preventive measure in cerebral infarction [A31932]. … Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones.
Categories: Vasodilators Used in Cardiac DiseasesProducts: MOLSIDOMIN 8 RET 1A PHARMABile acid-CoA:amino acid N-acyltransferase
go.drugbank.com/bio_entities/BE0002303TargetEnzymeHumansCatalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PubMed:12239217, PubMed:12810727, PubMed:2037576, PubMed:8034703). More than 95% of the BAs are N-acyl amidates with glycine and taurine (PubMed:803470...
Synonyms: BACATTechnetium Tc-99m tetrofosmin
go.drugbank.com/drugs/DB09160ApprovedTechnetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. … It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit which yields an injection.
Categories: Compounds used in a research, industrial, or household settingMechlorethamine
go.drugbank.com/drugs/DB00888ApprovedInvestigationalA vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. … The FDA granted marketing approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL
Synonyms: 2,2'-dichloro-N-methyldiethylamine, N-methyl-bis(2-chloroethyl)amineCategories: Compounds used in a research, industrial, or household setting