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Displaying results 1321 - 1330 of 10000 in total
  1. Drug

    Moclobemide

    go.drugbank.com/drugs/DB01171
    ApprovedInvestigational

    A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (

    Synonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamideCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Monoamine Oxidase A Inhibitors
  2. Drug

    Vidutolimod

    go.drugbank.com/drugs/DB17500
    Investigational

    Vidutolimod is a Toll-like receptor 9 (TLR9) agonist. It is an investigational cancer vaccine.

    Synonyms: Dna, d(g-g-g-g-g-g-g-g-g-g-g-a-c-g-a-t-c-g-t-c-g-g-g-g-g-g-g-g-g-g), Cmp-001 component cpg-a oligodeoxynucleotide tlr9 agonist
  3. Drug

    ATH434

    go.drugbank.com/drugs/DB16965
    ApprovedInvestigational

    Synonyms: 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-oneCategories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Inosine pranobex

    go.drugbank.com/drugs/DB13156
    Approved

    Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.

    Synonyms: Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3)Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Evorpacept

    go.drugbank.com/drugs/DB17573
    Investigational

    Evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).

    Synonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain
  6. Drug

    Tolbutamide

    go.drugbank.com/drugs/DB01124
    Approved

    Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

    Synonyms: N-(4-Methylphenylsulfonyl)-N'-butylurea, N-(4-Methylbenzenesulfonyl)-N'-butylureaCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  7. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Mixtures: SEFKLAV 250/62.5 MG EFERVESAN TABLET, 20 ADET, SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADETCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection. … Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection.

    Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET, VIRONTAR N COMPRIMIDOS RECUBIERTOSCategories: Antivirals used in combination for the treatment of HIV infections, P-glycoprotein inducers
  9. Drug

    Ocaratuzumab

    go.drugbank.com/drugs/DB17359
    Investigational

    Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.

    Synonyms: Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte surface antigen Leu-16, membrane-spanning 4-domains subfamily A member 1))
  10. Drug

    Nitrendipine

    go.drugbank.com/drugs/DB01054
    ApprovedWithdrawn

    Nitrendipine is a calcium channel blocker with marked vasodilator action. … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.

    Mixtures: ENEAS® 10/20 MG COMPRIMIDOS, ENEAS® 10/20 MG COMPRIMIDOSCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates