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Displaying results 1331 - 1340 of 10000 in total
  1. Drug

    Reboxetine

    go.drugbank.com/drugs/DB00234
    ApprovedInvestigationalWithdrawn

    Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine. … Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: เอ็ดโดรแน็กซ์ (4 มก.), Edronax 4 mg - Tabletten
  2. Drug

    Topotecan

    go.drugbank.com/drugs/DB01030
    ApprovedInvestigational

    It works by inhibiting DNA topoisomerases, type I.

    Synonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinCategories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic Index
  3. Drug

    Nabumetone

    go.drugbank.com/drugs/DB00461
    Approved

    [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen]. … Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).

    Mixtures: NuDroxiPAK N-500Categories: COX-2 Inhibitors, Cytochrome P-450 Substrates
  4. Drug

    AR-9281

    go.drugbank.com/drugs/DB06345
    Investigational

    AR-9281 inhibits soluble epoxide hydrolase.

  5. Drug

    Natamycin

    go.drugbank.com/drugs/DB00826
    ApprovedInvestigational

    Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. [PubChem]

    International brands: N-MycinProducts: NATACYN ® 5% SUSPENSION OFTALMICA ESTERIL, FUKRICIN 5%
  6. Drug

    Clofazimine

    go.drugbank.com/drugs/DB00845
    ApprovedInvestigationalWithdrawn

    Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of leprosy. … treatments such as [rifampicin] and [isoniazid].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: CLOFZIMIN® 100 MG
  7. Drug

    MW33

    go.drugbank.com/drugs/DB16358
    Experimental

    MW33 is a recombinant fully human antibody to SARS-CoV-2. … [L27411] This antibody injection is currently being investigated against COVID-19 in the clinical trial NCT04533048 (A Clinical Study to Evaluate MW33 Injection).

  8. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818]. … [A39983] This drug is frequently known as _Humira_. It is produced by recombinant DNA technology using a mammalian cell expression system.

    Products: AMGEVITA 40MG ILO I E FER, AMGEVITA 40MG ILO I E PEN
  9. Drug

    Virginiamycin M1

    go.drugbank.com/drugs/DB01669
    Experimental

    Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.

    Categories: Streptogramin Group ASynonyms: Mikamycin A, Ostreogrycin A
  10. Drug

    Piperaquine

    go.drugbank.com/drugs/DB13941
    ApprovedInvestigational

    Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550]. … Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and artemisinin derivatives became available.

    Synonyms: 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propaneMixtures: D-ARTEPP, D-ARTEPP DISPERSIBLE