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Displaying results 1341 - 1350 of 10000 in total
  1. Drug

    Hydroxyethyl cellulose

    go.drugbank.com/drugs/DB11602
    Approved

    It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. … It is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic

  2. Drug

    Thrombin alfa

    go.drugbank.com/drugs/DB11572
    Approved

    The cell culture process used in the manufacture of Thrombin Alfa employs no additives of human or animal origin. … approved by certain organizations like the European Medicines Agency [L2079].

  3. Drug

    Gilteritinib

    go.drugbank.com/drugs/DB12141
    ApprovedInvestigational

    [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018.

  4. Drug

    Isoxicam

    go.drugbank.com/drugs/DB08942
    ApprovedWithdrawn

    Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.

    Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDS
  5. Target

    Sigma non-opioid intracellular receptor 1

    go.drugbank.com/bio_entities/BE0000290
    TargetHumans

    Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the...

    Polypeptides: Sigma non-opioid intracellular receptor 1Synonyms: Sigma non-opioid intracellular receptor 1
  6. Target

    Non-receptor tyrosine-protein kinase TYK2

    go.drugbank.com/bio_entities/BE0004146
    TargetHumans

    Non-membrane spanning protein tyrosine kinase involved in numerous cytokines and interferons signaling, which regulates cell growth, development, cell migration, innate and adaptive immunity (PubMed:10542297

    Polypeptides: Non-receptor tyrosine-protein kinase TYK2
  7. Drug

    Smallpox (Vaccinia) Vaccine, Live

    go.drugbank.com/drugs/DB14711
    ApprovedInvestigational

    The New York City Board of Health strain of _Vaccinia_ is a viral strain used as a component of some smallpox vaccinations. … [L12747] ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007, contains live antigens of this strain.

    Synonyms: Vaccinia virus strain new york city board of health live antigen, Vaccinia virus strain new york city board of health live (attenuated) antigen
  8. Drug

    Alirocumab

    go.drugbank.com/drugs/DB09302
    ApprovedInvestigational

    Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of

    Categories: Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia
  9. Drug

    Darolutamide

    go.drugbank.com/drugs/DB12941
    ApprovedInvestigational

    Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). … [A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887]

    Categories: Antiandrogens, non-steroidal
  10. Drug

    Atogepant

    go.drugbank.com/drugs/DB16098
    ApprovedInvestigational

    [L38814] While its approval was predated by two other members of the same drug family, namely [ubrogepant] and [rimegepant], these agents are indicated only for abortive migraine therapy - atogepant is … It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021.