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Ibrexafungerp
go.drugbank.com/drugs/DB12471Approved[A235384,A235389] Similar to echinocandins, ibrexafungerp targets the fungal β-1,3-glucan synthase, which is not present in humans, limiting the chance of renal or hepatic toxicity. … [A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole antifungals.
Synonyms: (1S,4AR,6AS,7R,8R,10AR,10BR,12AR,14R,15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL-8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5-(PYRIDIN-4-YL)-1H-1,2,4- TRIAZOL-1-YL)-1,6,6A,7,8,9,10,10A,10BUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid. … [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996.
Products: URSOMED 250 MG/5 ML ORAL SÜSPANSİYON, 100 ML, URSOFALK 250 MG/5 ML SUSPANSIYON, 250 MLSodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigationalin May 2023. … [L46302] In some countries, sodium oxybate has been investigated and used in alcohol withdrawal syndrome (AWS) to aid abstinence maintenance in alcohol use disorders.[A251440, A251445]
Products: XYREM 500MG/ ML ORAL ÇÖZELTI, Natriumoxybat Kalceks 500 mg/ml Lösung zum EinnehmenLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
International brands: Kaopectate IIMixtures: Doc in the Box All Day SupplyGlipizide
go.drugbank.com/drugs/DB01067ApprovedInvestigationalIt was first introduced in 1984 [A179491] and is available in various countries including Canada and the U.S. … Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus.
Categories: Drugs Used in DiabetesProducts: Glipizide XL, Glucotrol XLMitapivat
go.drugbank.com/drugs/DB16236ApprovedInvestigationalMitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. … [A245478] On January 5, 2026, the FDA also approved the use of in the treatment of anemia in adults with alpha- or beta-thalassemia, making it the first oral treatment for this condition.[L54953]
Synonyms: Pkr-in-1Cholestyramine
go.drugbank.com/drugs/DB01432ApprovedInvestigationalCholestyramine resin is quite hydrophilic, but insoluble in water. … Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins.
Categories: Compounds used in a research, industrial, or household settingEnzacamene
go.drugbank.com/drugs/DB11219ApprovedIt is used in cosmetic products such as sunscreen to provide skin protection against UV rays. … While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and cosmetic products is approved by Health Canada.
Mixtures: Outback 2-in-1 Insect Repellent and Protective Sunscreen, Anthelios L-lait Ecran Intol.solaire SPF 60Synonyms: Enzacamene D-L form, 3-(p-Methylbenzylidene)-DL-camphorPentastarch
go.drugbank.com/drugs/DB09111ApprovedWithdrawnIt is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. … When administered, pentastarch remains mainly in the circulatory system and hence, it is considered a plasma expander.
Categories: Compounds used in a research, industrial, or household settingQuinidine
go.drugbank.com/drugs/DB00908Approved[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute conversion of atrial fibrillation to normal sinus rhythm. … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species.
Synonyms: (R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol, (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanolCategories: Antiarrhythmics, Class I, Antiarrhythmics, Class Ia