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Carfentanil
go.drugbank.com/drugs/DB01535IllicitInvestigationalVet approvedIt is marketed under the trade name Wildnil as a general anaesthetic agent for large animals. … Carfentanil is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans.
Categories: Heterocyclic Compounds, 1-Ring3-Methylfentanyl
go.drugbank.com/drugs/DB01571ExperimentalIllicit3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be between 400-6000 … times more potent than morphine in certain cases. 3-Methylfentanyl was initially discovered in 1974 and widespread illegal use of this drug has occurred since this time.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-MFAloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalIt is a perennial succulent xerophyte with elongated leaves that contain a clear gel. … Common active polysaccharides include glucomannans, polymannose, and acemannan, or b-(1–4)-acetylated polymannose [A32475].
Mixtures: Alcortin A, Alcortin AProducts: Secret No 1Sacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigational[A193671] One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2 (TROP-2) antibody with the topoisomerase I inhibitor SN-38. … [A193653] In November 2021 and July 20 2023, sacituzumab govitecan was also approved by the European Commission and Health Canada respectively.[L39372,L47601]
Categories: Trop-2-Directed Monoclonal AntibodiesProducts: TRODELVY®, TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADETBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigationalBudesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. … [L10598] It is also available in a combination product with [formoterol].[L10619]
Mixtures: DUORESP SP 320/9UG 1X60ED, DUORESP SP 320/9UG 1X60EDCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesMethenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedMethenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Mixtures: Urin D/S, Uretron D/SProducts: NETURONE GRANUL LIBA, 70 G, NETURONE GRANUL LIBA, 105 GValerian
go.drugbank.com/drugs/DB13196ApprovedValerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. … [DB00313] is a derivative of valeric acid, which is obtained from the plant root.
Mixtures: S. R. Formula, Lapidar 7 TabProducts: Sleep-eze V Natural CapletsSilicon dioxide
go.drugbank.com/drugs/DB11132ApprovedColloidal silica is also used as a wine, beer, and juice fining agent or stabilizer. … It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals.
Mixtures: DOCTRUST ONE S Tooth, DOCTRUST ONE S ToothCategories: Compounds used in a research, industrial, or household settingTrametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigational[L45583] Trametinib is currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and thyroid cancer, as monotherapy or in combination with [dabrafenib], a … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesProducts: MEKINIST®2 MG TABLETAS RECUBIERTAS, MEKINIST 2 MG FILM KAPLI TABLET ,7 TABLETIrofulven
go.drugbank.com/drugs/DB05786InvestigationalPhase III clinical trials involving the drug have been underway since early 2001 at sites in the U.S. and Europe. … A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track
Synonyms: 6-hydroxymethylacylfulvene