Search
Isoxicam
go.drugbank.com/drugs/DB08942ApprovedWithdrawnIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSSigma non-opioid intracellular receptor 1
go.drugbank.com/bio_entities/BE0000290TargetHumansFunctions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the...
Polypeptides: Sigma non-opioid intracellular receptor 1Synonyms: Sigma non-opioid intracellular receptor 1Non-receptor tyrosine-protein kinase TYK2
go.drugbank.com/bio_entities/BE0004146TargetHumansNon-membrane spanning protein tyrosine kinase involved in numerous cytokines and interferons signaling, which regulates cell growth, development, cell migration, innate and adaptive immunity (PubMed:10542297
Polypeptides: Non-receptor tyrosine-protein kinase TYK2Smallpox (Vaccinia) Vaccine, Live
go.drugbank.com/drugs/DB14711ApprovedInvestigationalThe New York City Board of Health strain of _Vaccinia_ is a viral strain used as a component of some smallpox vaccinations. … [L12747] ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007, contains live antigens of this strain.
Synonyms: Vaccinia virus strain new york city board of health live antigen, Vaccinia virus strain new york city board of health live (attenuated) antigenAlirocumab
go.drugbank.com/drugs/DB09302ApprovedInvestigationalAlirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of
Categories: Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaDarolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigationalDarolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). … [A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887]
Categories: Antiandrogens, non-steroidalAtogepant
go.drugbank.com/drugs/DB16098ApprovedInvestigational[L38814] While its approval was predated by two other members of the same drug family, namely [ubrogepant] and [rimegepant], these agents are indicated only for abortive migraine therapy - atogepant is … It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021.
Sparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigationalFurthermore, it is the first non-immunosuppressive therapy for the reduction of proteinuria in IgAN.[L45315] The use of sparsentan may cause hepatotoxicity and embryo-fetal toxicity. … >A</sub>R and 0.8 nM for AT<sub>1</sub>R).
Samarium (153Sm) lexidronam
go.drugbank.com/drugs/DB05273ApprovedRadiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium Sm 153 lexidronam is used to help … Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical.
Categories: Analgesics, Non-NarcoticNadroparin
go.drugbank.com/drugs/DB08813ApprovedInvestigationalWithdrawnNadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. … Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
Categories: Heparin (Low Molecular Weight)