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Pegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigational[A235000] Pegcetacoplan for subcutaneous use was granted FDA approval on 14 May 2021. … [A235000,A235005] Pegcetacoplan was developed out of a need for an inhibitor of complement mediated hemolysis further upstream of C5.
Indapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigationalagents may be required in order to achieve blood pressure targets. … [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally.
Categories: Antihypertensive Agents Indicated for Hypertension, Cytochrome P-450 SubstratesDrometrizole trisiloxane
go.drugbank.com/drugs/DB11585ApprovedThe compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia … relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as being generally recognized as safe and effective for
Mixtures: Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types, Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin TypesFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalFinasteride is an orally active drug that was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or … the need for surgical procedures.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Ran-finasteride, Van-finasterideDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a l...
Mixtures: CONGESTEX MAX ®, BUCOXOL ® GRIP MAX CAPSULAS DURAS CON CONTENIDO LIQUIDOCategories: Antihistamines for Systemic Use, P-glycoprotein inhibitorsAlmasilate
go.drugbank.com/drugs/DB13595ApprovedAlmasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However...
Categories: Drugs for Acid Related DisordersMagnesium gluconate
go.drugbank.com/drugs/DB13749ApprovedWithdrawnMagnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used as an ingredient in some medicines (such as antacids … In addition, it has been studied for its effects on premature uterine contractions [A32808].
Olaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigationalOlaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2. PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in c...
Categories: Cytochrome P-450 CYP2B6 Inducers, P-glycoprotein inhibitorsEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigationalThe intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to … [L5593] Esketamine may prove to be a promising treatment for patients diagnosed with major depressive disorder who have not experienced an improvement in symptoms despite treatment with various medications
Categories: Antidepressive Agents Indicated for Depression, NMDA Receptor AntagonistsGallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigationalprostate cancer or in patients who may have recurrent prostate cancer. … [L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer.[L45598]