Drometrizole trisiloxane

DB11585ApprovedSmall molecule

Drometrizole trisiloxane is an UV ray absorbing agent used in sunscreens to protect skin from UV radiation. Drometrizole trisiloxane is a photostable UVA and UVB light filter.

Chemical structure of Drometrizole trisiloxane
Mechanism
Curator reviewed · 23 references
Primary indication
Drometrizole trisiloxane is used as an active ingredient in various sunscreens for the indication of protecting the skin by absorbing the damaging UV radiation of sunlight.Curator reviewed · 1 structured indication
Formula / weight
C24H39N3O3Si3 · 501.849 g/mol (avg)
First approval
Canada, 2006
Also known as
Silatrizole
Code names
OR-10154

Resolves to

Clinical / RWD
Structure
InChIKeyHUVYTMDMDZRHBN-UHFFFAOYSA-NSMILESCC(CC1=C(O)C(=CC(C)=C1)N1N=C2C=CC=CC2=N1)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

What you can answer from here — as of August 31, 2026

3Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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157Marketed productsAcross 2 countries and 7 labellers
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10+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Drometrizole trisiloxane, and which companies have late-stage candidates in those indications?

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