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Displaying results 1361 - 1370 of 10000 in total
  1. Target

    Mitogen-activated protein kinase kinase kinase kinase 5

    go.drugbank.com/bio_entities/BE0009474
    TargetHumans

    May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway

    Synonyms: MEK kinase kinase 5
  2. Drug

    Iron

    go.drugbank.com/drugs/DB01592
    ApprovedInvestigational

    Iron is used to build up the blood in anemia. … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems.

    Mixtures: Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap, KORDEL`S NUTRITIME TABLETProducts: HEMBIN®, EUROFER® JARABE
  3. Drug

    Enlicitide

    go.drugbank.com/drugs/DB22580
    ApprovedInvestigational

    [L63795] Enlicitide was developed by Merck Sharp & Dohme and received initial U.S. approval in 2026, marketed under the trade name LIPFENDRA.[L63795] … Enlicitide is a macrocyclic peptide inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).

  4. Drug

    Simethicone

    go.drugbank.com/drugs/DB09512
    ApprovedInvestigational

    [A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308] … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.

    Mixtures: MUVETT S, MUVETT SCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Capsicum oleoresin

    go.drugbank.com/drugs/DB11131
    Approved

    When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary spice. … It is suggested that capsicum oleoresin is a rich source of phytochemicals that consist of phenolic compounds with antioxidant and antidiabetic activities [A32317].

    Mixtures: SLOAN`S ANALGESIC RUB
  6. Drug

    Brexanolone

    go.drugbank.com/drugs/DB11859
    ApprovedInvestigational

    As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically … Since PPD, like various other types of depression, is characterized by feelings of sadness, worthlessness or guilt, cognitive impairment, and/or possibly suicidal ideation, it is considered a life-threatening

    Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator, Neuroactive Steroid Gamma-Aminobutyric Acid (GABA) A Receptor Positive Modulators
  7. Target

    Dual specificity mitogen-activated protein kinase kinase 1

    go.drugbank.com/bio_entities/BE0000870
    TargetHumans

    Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates...

    Synonyms: MEK 1
  8. Drug

    Loracarbef

    go.drugbank.com/drugs/DB00447
    ApprovedWithdrawn

    Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    GC-376 free acid

    go.drugbank.com/drugs/DB15796
    Experimental

    The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov infections[A219036,A219056]. … GC-376 is a 3C-like protease (3CL<sup>pro</sup> or M<sup>pro</sup>) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Benzylpenicillin

    go.drugbank.com/drugs/DB01053
    ApprovedInvestigationalVet approved

    Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans*, and *Enterococcus faecalis*. … Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci

    Synonyms: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-phenylacetamido)penicillanic acidMixtures: SENCAIN-S 100.000 IU/300.000 IU IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL, Bicillin C-R 900/300