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Displaying results 1371 - 1380 of 10000 in total
  1. Drug

    Dexrazoxane

    go.drugbank.com/drugs/DB00380
    ApprovedInvestigationalWithdrawn

    It appears to inhibit formation of a toxic iron-anthracycline complex. … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing activation of the GPIIb/IIIa receptor complex. … Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727.

    Products: PRASUGREL AL 5MG HBR FTA, PRASUGREL AL 10MG HBR FTA
  3. Drug

    Dimercaprol

    go.drugbank.com/drugs/DB06782
    Approved

    In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects.

    Categories: Compounds used in a research, industrial, or household settingInternational brands: Bal In Oil Injection
  4. Drug

    Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB15703
    ApprovedInvestigational

    Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses.

    Mixtures: Fluarix Tetra Injektionssuspension in einer Fertigspritze, VaxigripTetra Injektionssuspension in einer FertigspritzeSynonyms: Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated)
  5. Drug

    Lifitegrast

    go.drugbank.com/drugs/DB11611
    ApprovedInvestigational

    It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. … The ophthalmic solution was approved in July, 2016 under the trade name Xiidra.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Cetylpyridinium

    go.drugbank.com/drugs/DB11073
    ApprovedInvestigational

    Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. … In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.

    Mixtures: Kank-A, TANTUM VERDE GENGIVITE E STOMATITECategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Sulisobenzone

    go.drugbank.com/drugs/DB11185
    Approved

    As a group, benzophenones may be used to delay photodegradation or extend shelf life in toiletries and plastic surface coatings [L2671]. … The benzophenones are a group of aromatic ketones that have both pharmaceutical and industrial applications [L2671]. Benzophenones may be found organically in fruits such as grapes [L2669].

    Mixtures: 3-IN-1 Active Moisturizer
  8. Drug

    Corynebacterium diphtheriae

    go.drugbank.com/drugs/DB09877
    ApprovedInvestigational

    The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. … The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.

    Mixtures: Boostrix Injektionssuspension in einer Fertigspritze, Boostrix Polio - Injektionssuspension in einer Fertigspritze
  9. Drug

    Aprocitentan

    go.drugbank.com/drugs/DB15059
    ApprovedInvestigational

    [L50261] It was the first antihypertensive employing a novel mechanism to be approved in almost 40 years.[L50261] … [A263386,L50261] Aprocitentan was approved by the FDA in March 2024 for the treatment of hypertension in patients inadequately controlled with standard therapy.

  10. Drug

    Attapulgite

    go.drugbank.com/drugs/DB01574
    ApprovedVet approvedWithdrawn

    Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications.

    Categories: Compounds used in a research, industrial, or household setting