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Displaying results 1381 - 1390 of 4588 in total
  1. Pathway

    Neostigmine Action Pathway (new)

    smpdb.ca/view/SMP0126669
    Drug action

    Neostigmine is a cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. Cholinergic neurons in the brain are primarily responsible for movement in skeletal muscles. In the neuron, acetyl...

    Drugs: Choline · Calcium · Magnesium cation · Neostigmine · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  2. Pathway

    Ambenonium Action Pathway (new)

    smpdb.ca/view/SMP0126691
    Drug action

    Ambenonium is a cholinesterase inhibitor used in the treatment of myasthenia gravis, helping to alleviate muscle weakness by stimulating muscle contraction and stimulation. Its mechanism of action is through reversible inhibition of acet...

    Drugs: Choline · Ambenonium · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  3. Pathway

    Malathion Action Pathway

    smpdb.ca/view/SMP0126697
    Drug action

    Malathion is a cholinesterase inhibitor used to treat head lice due to its low toxicity to humans. Malathion is an organophosphate which acts to inhibit acetylcholinesterase activity, it acts by binding to cholinesterase stopping the bre...

    Drugs: Choline · Malathion · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  4. Drug

    Equine Botulinum Neurotoxin E Immune FAB2

    go.drugbank.com/drugs/DB13897
    Approved

    Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E. It is intravenously administered for the treat...

  5. Drug

    Equine Botulinum Neurotoxin C Immune FAB2

    go.drugbank.com/drugs/DB13898
    Approved

    Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C. It is intravenously administered for the treat...

  6. Drug

    Peginterferon alfa-2a

    go.drugbank.com/drugs/DB00008
    ApprovedInvestigational

    SVR and eradication of HCV infection is associated with significant long-term health benefits including reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma … Approved in 2002 by the FDA, Pegasys is indicated for the treatment of HCV with [DB00811] or other antiviral drugs [FDA Label].

  7. Drug

    Elosulfase alfa

    go.drugbank.com/drugs/DB09051
    ApprovedInvestigational

    It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™.

  8. Drug

    Artenimol

    go.drugbank.com/drugs/DB11638
    ApprovedInvestigational

    Artemisinin combination therapy is highly effective against malaria and stongly recommended by the World Health Organization [L1156]. … It was first authorized for market by the European Medicines Agency in October 2011 in combination with [DB13941] as the product Eurartesim.

  9. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.

  10. Drug

    Melatonin

    go.drugbank.com/drugs/DB01065
    ApprovedInvestigationalNutraceuticalVet approved

    pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus) but … In mammals, melatonin is produced by the pineal gland.