Search
LNP-nCoVsaRNA Vaccine
go.drugbank.com/drugs/DB15799ExperimentalThe vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly funded by UK Research and Innovation. … LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells.
Levonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigational[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.
Products: ONIVE 1® 1.5 MG TABLETA, ONIVE 2® 0.75 MG TABLETASGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects. … [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by
International brands: U-gencinProducts: GENTAMED G/K 5 ML DAMLA, GENTAMICINA MK 60MG/1.5ML.Antrafenine
go.drugbank.com/drugs/DB01419ApprovedIt is not widely used as it has largely been replaced by newer drugs. … Antrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen.
Unexpanded umbilical cord-derived allogeneic CD34- hematopoietic stem cells
go.drugbank.com/drugs/DB28348Approved[L54106] Zemcelpro also contains [dorocubicel], a preparation CD34+ HSCs derived from the same cord blood sample and expanded _ex vivo_ using [UM-171].
Safflower oil
go.drugbank.com/drugs/DB09446ApprovedInvestigationalWithdrawnGamma linolenic acid (GLA) safflower oil is marketed as an over-the-counter dietary supplement. … Safflower oil with a higher content of polyunsaturated fatty acids is more commonly used as an edible oil.
Mixtures: Carthaphy CapLisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigational[A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first approved by the FDA in April 2008.[A2230] It was also approved by Health Canada in February 2009. … [L48285] Lisdexamfetamine works to treat attention deficit hyperactivity disorder and binge eating disorder [A2230] by blocking dopamine and norepinephrine reuptake and increasing their levels in the extraneuronal
Clozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other side effects, notably gastrointestinal hypomotility and orthostatic hypotension. [L905,A215552]. … [A256718] Clozapine was approved by the FDA in 1989 for treatment-resistant schizophrenia under the brand CLOZARIL.
Inosine
go.drugbank.com/drugs/DB04335ApprovedA purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. … It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules.
Idelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalMore specifically, idelalisib targets P110δ, the delta isoform of the enzyme phosphatidylinositol-4,5-bisphosphate 3-kinase, also known as PI-3K. … By inhibiting this enzyme, idelalisib induces apoptosis of malignant cells and inhibits several cell signaling pathways, including B-cell receptor (BCR) signaling and C-X-C chemokine receptors type 5 and