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Pyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigationalBy inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and relieve symptoms. … muscle tone loss, muscle weakness, and fatigue.
Products: Mestinon Tablet 10mg, Regonol Inj 5mg/mlDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Mixtures: Aerius D-12 Modified Release Tablets 2.5mg/120mg, AXIVOL PLUS 2.5 MG / 120MG EFERVESAN TABLET, 20 ADETCategories: Loratadine and derivativesXanthinol
go.drugbank.com/drugs/DB09092ApprovedWithdrawn[L1079] Xaninthol is known to be a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose metabolism resulting in an increased energy … [L1080] It was approved as a drug in 1998 in Canada and nowadays its status is cancelled post marketing.
Products: Complamin Tab 150mgLimaprost
go.drugbank.com/drugs/DB09211InvestigationalLimaprost alfadex was discovered from collaborative research between Ono Pharmaceutical (Ono) and Dainippon Sumitomo Pharma (DSP). … Prostaglandins have a wide variety of actions, including, but not limited to muscular constriction and mediation of inflammation.
Categories: Blood and Blood Forming OrgansProducts: OPALMON TABLETS 5 ugEpinastine
go.drugbank.com/drugs/DB00751Approvedto both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding
Categories: Decongestants and AntiallergicsProducts: FLURINOL® COMPRIMIDOS RECUBIERTOS 20MGInotuzumab ozogamicin
go.drugbank.com/drugs/DB05889ApprovedInvestigational[A20352] The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly releases N-acetyl-gamma-calicheamicin dimethylhydrazide, which produces cytotoxic effects … Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: BESPONSA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1MG/VIALRosiglitazone
go.drugbank.com/drugs/DB00412ApprovedInvestigationalApart from its effect on insulin resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and inhibitor (IκB) levels increase in patients on rosiglitazone. … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl).
Categories: Alimentary Tract and Metabolism, metformin and rosiglitazoneProducts: Avandia 2mgCefpodoxime
go.drugbank.com/drugs/DB01416ApprovedInvestigationalVet approvedCommonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. … Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria.
Products: CEFPODOXIM AL 100MG, CEFPODOXIM - CT 100MGErgoloid mesylate
go.drugbank.com/drugs/DB01049Approved[A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued. … [L2639]Later in 1991, the mixture of ergoloid mesylates was retaken by Sun Pharmaceutical Industries and approved by the FDA.
Categories: Ergot Alkaloids and DerivativesProducts: Hydergine Tablets, 1mgIsradipine
go.drugbank.com/drugs/DB00270ApprovedIsradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and arterial smooth muscle cells. … It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class.
Categories: Calcium-Regulating Hormones and AgentsProducts: ISRADIPINO 2.5MG TABLETAS, VASCAL UNO 5MG