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Displaying results 131 - 140 of 13788 in total
  1. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric patients with congenital factor IX deficiency (Hemophilia B). … It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX.

    Synonyms: Recombinant factor IX, Factor IX (Recombinant)Products: CONCENTRADO DE FACTOR IX, BeneFIX powder and solvent for solution for injection 500 IU/VIAL.
  2. Drug

    Fosfomycin

    go.drugbank.com/drugs/DB00828
    ApprovedInvestigational

    [A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. … [A230348] As such there is great interest in exploring the usefulness of fosfomycin for indications beyond the treatment of UTIs.[A230353,A230358]

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: FOSMICIN FOR I.V. USE, Fosfomycin Powder for Oral Solution
  3. Drug

    Dextrose, unspecified form

    go.drugbank.com/drugs/DB09341
    ApprovedInvestigationalVet approved

    It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. … It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level.

    Synonyms: Dextrose, unspecified formMixtures: Braun 5% Dextrose in 0.3% Sodium Chloride for Intravenous Infusion, DEXTROSE 5% IN NS 0.9% INJ 1000ML
  4. Drug

    Polymyxin B

    go.drugbank.com/drugs/DB00781
    ApprovedInvestigationalVet approved

    Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. … It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].

    Mixtures: Water-Jel 3-in-1 Antibiotic, Zee 3-in-One First Aid AntibioticCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  5. Drug

    Linperlisib

    go.drugbank.com/drugs/DB17235
    Investigational

    Synonyms: -in-2, N-(5-(6-fluoro-8-((4-(2-hydroxypropan-2-yl) piperidin-1-yl)methyl)-2-morpholinoquinazolin-4-yl)-2-methoxypyridin-3-)methanesulfonamide
  6. Drug

    Human Rho(D) immune globulin

    go.drugbank.com/drugs/DB11597
    Approved

    It was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune thrombocytopenic purpura (ITP) in adults. … Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn).

    Synonyms: Rho(D) immune globulin IM human, Immunoglobulin human anti-RHMixtures: Winrho Sd Kit Inj, Winrho Sd Kit Inj.
  7. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.

    Mixtures: Benylin for Children All-IN-one Cold & Fever, Benylin for Children All-IN-one Cold and FeverCategories: Nasal Decongestants for Systemic Use, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  8. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered doses.[A39983] Several biosimilars to adalimumab. … A high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases.

    Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: IDACIO SOLUTION FOR INJECTION IN PRE-FILLED PEN 40MG/0.8ML, IDACIO SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 40MG/0.8ML
  9. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA). … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids.

    Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: Enbrel Solution for Injection in a Pre-filled Pen 50mg, NEPEXTO 50mg/ml Solution for Injection in Pre-Filled Pen
  10. Drug

    Colistimethate

    go.drugbank.com/drugs/DB01111
    ApprovedInvestigationalVet approved

    Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. … Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.

    Products: COLINTENSIN 1M UI, COLINTENSIN 2M UI