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Azathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Products: AZATHIOPRIN AL 25MG FTA, AZATHIOPRIN AL 50MG FTACat dander extract
go.drugbank.com/drugs/DB13904ApprovedIt is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. … An allergic reaction to cats is induced by the presence of antigen-specific IgE antibodies that are bound to specific receptors on mast cells and basophils.
Products: Standardized Cat Hair ApPiretanide
go.drugbank.com/drugs/DB02925ApprovedPiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in … an aromatic nucleus in the presence of other aromatically bonded functional groups.
Mixtures: RAMITANID AL 5MG/6MGProducts: PIRETANID AL 6MG TABLETTENMoxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnAs well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome. … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension.
Categories: Imidazoline Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsProducts: MOXONIDIN AL 0.2MG FILMTAB, MOXONIDIN AL 0.3MG FILMTABPipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnHowever, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.
Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor AntagonistsProducts: PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG).Dorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380] … [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: DORZOLAMID AL COMP ATR, DORZOLAMID AL COMP ATRProducts: DORZOLAMID AL 20 MG/ML, Monosopt Eye Drops [Dorzolamide Hydrochloride Eye Drops, Solution (2 % w/v as Dorzolamide)]Trimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: TRIMIPRAMIN AL 25MG TABL, TRIMIPRAMIN AL 100MG TABLBecaplermin
go.drugbank.com/drugs/DB00102ApprovedInvestigationalBecaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds.
Products: REGRANEX GEL AL 0.01%Sumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigationalSumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.
Categories: Monoamine Oxidase A Substrates, Serotonin Receptor AgonistsProducts: Ag-sumatriptan, SUMATRIPTAN AL 50MG FTAQuercus alba pollen
go.drugbank.com/drugs/DB10376ApprovedIt can be subcutaneously administered to initiate an immune response in case of an allergic reaction. … Quercus alba pollen, or oak white pollen, is a non-standardized allergen extract used for the diagnosis and treatment of allergic disease to grass pollen.
Products: Center-AL - Quercus Alba Pollen