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Displaying results 131 - 140 of 9617 in total
  1. Drug

    Milrinone

    go.drugbank.com/drugs/DB00235
    ApprovedInvestigational

    [A228333] It was approved by the FDA on December 31, 1987, and was marketed under the trademark PRIMACOR® by Sanofi-Aventis US before being discontinued.[L31483] … [A228338, A11759, A228323, A228333, A228348, L31483] Milrinone was originally synthesized at the Sterling Winthrop Research Institute in the 1980s.

    Products: MILRINONA 10MG/10ML, MILRINONE-BAXTER CONCENTRATED SOLUTION FOR INJECTION 10MG/10ML
  2. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, rosuvastatin is considered the most potent; doses of 10 to 40mg rosuvastatin per day were … Rosuvastatin is also a unique member of the class of statins due to its high hydrophilicity which increases hepatic uptake at the site of action, low bioavailability, and minimal metabolism via the Cytochrome

    Mixtures: ZENIBE® 10MG + 20MG TABLETAS RECUBIERTAS, ROSUVAXE ® 20/10MG TABLETAProducts: CRESTOR 10MG, ROSUSTAR 10MG
  3. Drug

    Guanethidine

    go.drugbank.com/drugs/DB01170
    ApprovedWithdrawn

    It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.

    Products: Guanethidine 10 Tab 10mg, Apo Guanethidine Sulfate Tab 10mg
  4. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.

    Products: FLUVASTATIN - CT 20MG HART, FLUVASTATIN - CT 40MG HART
  5. Drug

    Montelukast

    go.drugbank.com/drugs/DB00471
    ApprovedInvestigational

    since become available as a generic and as a brand name product. … Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.

    Mixtures: BROCRIPTIN® 5MG/2.5MGSynonyms: (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
  6. Drug

    Cladribine

    go.drugbank.com/drugs/DB00242
    ApprovedInvestigational

    [A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell … Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes.

    Products: Mavenclad 10mg Tablets, MAVENCLAD TABLET 10MG
  7. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized. … [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States.

    Mixtures: Exforge HCT Tablet 10mg/160mg/25mg, Amlodipin/Valsartan/HCT +pharma 10mg/160mg/25mg FilmtablettenProducts: PMS-valsartan, VALSARTAN CT 80MG
  8. Drug

    Famotidine

    go.drugbank.com/drugs/DB00927
    ApprovedInvestigational

    It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. … about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis.

    Mixtures: ETOPLUS 400MG/8MG/20MG FİLM KAPLI TABLET, 14 ADET, ETOFAM 400MG/20MG FİLM KAPLI TABLET, 20 ADETProducts: Famotidine 10mg, Pepcid I.V. 10mg/ml
  9. Drug

    Amitriptyline

    go.drugbank.com/drugs/DB00321
    ApprovedInvestigational

    Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]

    Mixtures: PMS-levazine 3/15 Tab, PMS-levazine 2/25 TabProducts: Elavil Tablet 10mg, Novo-triptyn Tab 10mg
  10. Drug

    Tolterodine

    go.drugbank.com/drugs/DB01036
    ApprovedInvestigational

    Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

    Products: DETRUSITOL 1MG, TOLTERODIN PFI 1MG