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Peginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalPeginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Peginterferon alfa-2b is available as a variable dose injectable product (tradename Pegintron) used for the treatment of chronic Hepatitis C.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2C9 InducersProducts: PEG-INTRON CLEARCLICK FOR INJECTION 150 mcg/0.5 ml, PEGINTRON 150 MCG ENJEKSIYONLUK COZELTI TOZU VE COZUCUSU, 4 ADETOxolamine
go.drugbank.com/drugs/DB13216ApprovedOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419].
Mixtures: KATARİN 250 MG/100 MG/2 MG KAPSÜL, 15 ADET, KATARIN 120 MG+50 MG+1 MG/5 ML PEDIATRIK SURUP 100 MLProducts: OXOTUSS ŞURUP 50 MG/5 ML, 120 ML, PERBRONS 10 MG 120 ML SURUPOxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A797] Due to this chemical moiety, oxaliplatin readily undergoes non-enzymatic biotransformation, thus complicating oxaliplatin's pharmacokinetics. … [A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination.
Categories: OCT2 Substrates with a Narrow Therapeutic IndexProducts: AL OXA ® SOLUCION CONCENTRADA PARA INFUSION, PLOXAL-S 150 MG/30 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON,1 ADETIomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigationalIomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use. … [A265090,A265095] Iomeprol first appeared in the market in 1994 [A265095] and is currently used in various diagnostic processes involving x-ray imaging and computed tomography (CT) scans.[L52260]
Categories: Compounds used in a research, industrial, or household settingProducts: IOMERON 350 INJECTION 350 mg/ml, IOMERON 150 100 ML FLAKONalpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003Approved= 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120]. … , males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males
Mixtures: Vitamin E 400 Iu and Selenium 25 Mcg Capsules, . & Selenium 50 Mcg CapsulesCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesCefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Mixtures: BIGCEF 250/125 MG FILM KAPLI TABLET, 10 ADET, BIGCEF 500/125 MG FILM KAPLI TABLET, 10 ADETProducts: Nu-cefuroxime, Cefuroxim Dr. Eberth 1500 mg Pulver zur Herstellung einer Injektions-/InfusionslösungRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigational[Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action.
Products: BROMURO DE ROCURONIO 50 MG/5ML., BROMURO DE ROCURONIO 50 MG /5MLEstradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approvedEthinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration. … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.
Synonyms: (17β)-estra-1,3,5(10)-triene-3,17-diol, 17β-estra-1,3,5(10)-triene-3,17-diolInternational brands: Estraderm MXTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalIt possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent. … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.
Products: Tranexamsäure Sanus 100 mg/ml Injektionslösung, Cyklokapron 100 mg/mlTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: Qvaya 1 mg/ml Emulsion zur Anwendung auf der Haut, PROGRAF® XL CAPSULAS DE LIBERACIONPROLONGADA DE 1 MG