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Displaying results 131 - 140 of 10000 in total
  1. Drug

    Tolcapone

    go.drugbank.com/drugs/DB00323
    ApprovedInvestigationalWithdrawn

    It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. … Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenone
  2. Drug

    Pyridoxal phosphate

    go.drugbank.com/drugs/DB00114
    ApprovedInvestigationalNutraceutical

    This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.

    Mixtures: Medi-10, Xyzbac GCategories: Heterocyclic Compounds, 1-Ring, Vitamin B Complex
  3. Drug

    Idoxuridine

    go.drugbank.com/drugs/DB00249
    ApprovedWithdrawn

    An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

    Categories: Heterocyclic Compounds, 1-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil
  4. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias. … [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications.

    Categories: Drug-Related Side Effects and Adverse Reactions, Metabolic Side Effects of Drugs and SubstancesSynonyms: 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansäure, 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
  5. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored.[L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide.

    Mixtures: LOSARBAY®- H COMPRIMIDOS RECUBIERTOS 50 MG / 12. 5 MG, ARAMAX ® 5/50 MG TABLETASCategories: Heterocyclic Compounds, 1-Ring, Angiotensin II Type 1 Receptor Blockers
  6. Drug

    Clioquinol

    go.drugbank.com/drugs/DB04815
    ApprovedVet approvedWithdrawn

    Clioquinol was withdrawn in 1983 due to neurotoxicity.

    Synonyms: 7-Iodo-5-chloroxine, 5-Chlor-7-jod-8-hydroxy-chinolinMixtures: LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 G
  7. Drug

    Euflavine

    go.drugbank.com/drugs/DB13326
    Investigational

    Synonyms: 3,6-diamino-10-methylacridinium chlorideCategories: Antiseptics and Disinfectants, Heterocyclic Compounds, 3-Ring
  8. Drug

    Latanoprost

    go.drugbank.com/drugs/DB00654
    ApprovedInvestigational

    Another benefit latanoprost is that it can be administered once a day.[A184490] … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol].

    Mixtures: Latanoprost comp ratiopharm 50 Mikrogramm/ml und 5 mg/ml Augentropfen, LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPSCategories: Prostaglandins F, Synthetic, Compounds used in a research, industrial, or household setting
  9. Drug

    XT-150

    go.drugbank.com/drugs/DB21756
    Investigational

    XT-150 is a locally injectable non-viral therapy expressing IL-10v, a proprietary modified variant of IL-10.[L52125] It is being developed by Xalud Therapeutics.

    Synonyms: non-viral human interleukin-10 (IL-10) variant (IL-10var) encoding plasmid deoxyribonucleic acid (pDNA)
  10. Drug

    Methylphenobarbital

    go.drugbank.com/drugs/DB00849
    Approved

    A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.

    Synonyms: 5-ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-ethyl-1-methyl-5-phenylbarbituric acidCategories: Heterocyclic Compounds, 1-Ring, Barbiturates and Derivatives