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Displaying results 131 - 140 of 8547 in total
  1. Drug

    Allopurinol

    go.drugbank.com/drugs/DB00437
    ApprovedInvestigational

    It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942].

    Products: CLINT TABLET 100MG, Purinol Tab 100mg
  2. Drug

    Leniolisib

    go.drugbank.com/drugs/DB16217
    ApprovedInvestigational

    Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a ...

    Synonyms: Cdz-173 free base, Cdz173 free base
  3. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    [L42880] It is a second-generation tetracycline that was first discovered in 1967.[A19429] Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines.

    Products: Mondoxyne NL 100mg, DOXYCAP 100MG
  4. Drug

    Clozapine

    go.drugbank.com/drugs/DB00363
    ApprovedInvestigational

    Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. … [A256718] Clozapine was approved by the FDA in 1989 for treatment-resistant schizophrenia under the brand CLOZARIL.

    Products: LEPONEX 100MG, Zapine Tablets 100mg
  5. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    [L11593] It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. … Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.

    Mixtures: CLINDAMICINA / CLOTRIMAZOL 100MG/200MG, CLINDAMICINA/KETOCONAZOL 100 MG/400MGProducts: INFEX 100MG CÁPSULA DE GELATINA BLANDA, SOBELIN 150MG
  6. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. … [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel antidiabetic drug.[A188330]

    Synonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamateProducts: Topamax 100mg, TOPAMAX 100MG
  7. Drug

    Fluorouracil

    go.drugbank.com/drugs/DB00544
    ApprovedInvestigational

    A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.

    Products: FLUOROURACIL-GRY 1000MG, 5 FU MEDAC 50MG/ML 1000MG
  8. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide. … [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]

    Mixtures: LOSAMLO 100MG/10MG FTA, LOSAMLO 100MG/10MG FTAProducts: LOSAR DENK 100MG, LOSARGAMMA 100MG
  9. Drug

    Nilutamide

    go.drugbank.com/drugs/DB00665
    ApprovedInvestigational

    To date, antiandrogen monotherapy has not consistently been shown to be equivalent to castration.

    Products: Anandron Tab 100mg, Anandron - Tab 100mg
  10. Drug

    Amoxapine

    go.drugbank.com/drugs/DB00543
    Approved

    Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an a...

    Products: Asendin Tab 100mg, Asendin - Tab 100mg