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Displaying results 1391 - 1400 of 10000 in total
  1. Drug

    Atazanavir

    go.drugbank.com/drugs/DB01072
    ApprovedInvestigational

    Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  2. Drug

    Migalastat

    go.drugbank.com/drugs/DB05018
    ApprovedInvestigational

    significant improvement in treating, diagnosing or preventing a serious condition over available therapies. … [L4274] Migalastat (approved and sold under Amicus Therapeutics' brand name Galafold) is subsequently an oral pharmacological chaperone of alpha-Gal A for the treatment of Fabry disease in adults who

    Categories: Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones
  3. Drug

    Temoporfin

    go.drugbank.com/drugs/DB11630
    Approved

    Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label]. … It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.

    Categories: Heterocyclic Compounds with 4 or More Rings
  4. Drug

    Retapamulin

    go.drugbank.com/drugs/DB01256
    Approved

    Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.

    Categories: Antibiotics for Topical Use
  5. Drug

    Ferrous gluconate

    go.drugbank.com/drugs/DB14488
    ApprovedInvestigational

    Mixtures: Alsimine W Vitamins A D, Multi-force for Women Tab
  6. Drug

    Technetium Tc-99m succimer

    go.drugbank.com/drugs/DB09436
    Approved

    Technetium Tc-99m succimer is used with gamma scintigraphy or single-photon emission computed tomography (SPECT). … Technetium Tc-99m (<sup>99m</sup>Tc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Estradiol valerate

    go.drugbank.com/drugs/DB13956
    ApprovedInvestigationalVet approved

    Estradiol Valerate (also known as E2V) is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located in

    Categories: Hormonal Contraceptives for Systemic Use
  8. Drug

    Bromodiphenhydramine

    go.drugbank.com/drugs/DB01237
    Approved

    Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.

    Categories: Antihistamines for Systemic Use
  9. Drug

    Umbralisib

    go.drugbank.com/drugs/DB14989
    ApprovedInvestigationalWithdrawn

    Unfortunately, many patients experience a relapse or develop resistance to these drugs. … While it initially offered a promising therapy for patients experiencing relapsing or refractory disease,[A229363] umbralisib was withdrawn from the market due to safety concerns as the drug was associated

  10. Drug

    Desflurane

    go.drugbank.com/drugs/DB01189
    ApprovedInvestigational

    Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as [methoxyflurane], [sevoflurane], [enflurane], or [isoflurane]. … It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285]