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Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
go.drugbank.com/bio_entities/BE0004551TargetHumansRecruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells … Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.
Polypeptides: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1Hepatitis C Infections
go.drugbank.com/conditions/DBCOND0072126Drugs: Interferon alfaSynonyms: Hep non-A non-B, Hepatitis non-A non-BRasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: (R)-N-2-Propynyl-1-indanamine, (1R)-N-propargylindan-1-amineRecurrent Miscarriages
go.drugbank.com/conditions/DBCOND0032265Drugs: DydrogesteroneSynonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy lossBiotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Synonyms: 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acidMixtures: Multiple Vitamins (Adult) Single Dose, Multiple Vitamins (Pediatric) Single Dose VialDiclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).
Synonyms: [2-(2,6-dichloroanilino)phenyl]acetic acid, 2-((2,6-dichlorophenyl)amino)benzeneacetic acidMixtures: Vopac MDS - Anti-Inflammatory Management Kit with Metered Dose Bottle, DermacinRx Lexitral PharmaPak IIAurothioglycanide
go.drugbank.com/drugs/DB19361ApprovedWithdrawnSynonyms: (2-mercapto-n-phenylacetamidato-o,s)gold, 2-mercaptoacetanilide s-gold derivativePalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalIt is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of … As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
Synonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingPolysorbate 80
go.drugbank.com/drugs/DB11063ApprovedInvestigationalPolysorbate 80 is a hydrophilic nonionic surfactant. It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops. … A substance that would not normally dissolve in a particular solution is able to dissolve with the use of a solubilizing agent.
Mixtures: i-Drops ARTIFICIAL TEARS, ENDURA® UDCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsIntermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure
go.drugbank.com/conditions/DBCOND0120023Drugs: DiazepamSynonyms: Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure