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Displaying results 1401 - 1410 of 10000 in total
  1. Drug

    Anethole

    go.drugbank.com/drugs/DB15916
    ApprovedWithdrawn

    Mixtures: Bentasil GreenCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Tannic acid

    go.drugbank.com/drugs/DB09372
    ApprovedInvestigational

    Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid.

    Categories: Compounds used in a research, industrial, or household settingProducts: Zilactin Medicated Gel 7%
  3. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism

    Synonyms: D-panthenol, (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamideMixtures: B-KOMP ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET, Alsimine W Vitamins A D
  4. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. … Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.

    Synonyms: 7(S)-Chloro-7-deoxylincomycin, Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranosideInternational brands: Dalacin C, Dalacin T Topical Solution
  5. Drug

    Dilmapimod

    go.drugbank.com/drugs/DB12140
    Investigational

    Dilmapimod (SB-681323) is a p38 MAP-kinase inhibitor that has potential uses in inflammatory conditions such as RA (Rheumatoid Arthritis). … Previous p38 MAP-kinase inhibitors have been hindered in development by liver toxicity. Methotrexate (common treatment for RA patients) also has potential liver toxicity.}

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Taberminogene vadenovec

    go.drugbank.com/drugs/DB05011
    Experimental

    Taberminogene vadenovec (EG004) is a novel product consisting of a local delivery device and a gene-based medicine, being developed to prevent the blocking of veins and arteries that frequently occurs … that their blood can be regularly filtered using a dialysis machine.

  7. Drug

    Finerenone

    go.drugbank.com/drugs/DB16165
    ApprovedInvestigational

    Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart … [A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449]

    Categories: Mineralocorticoid Receptor Antagonists, Cytochrome P-450 Substrates
  8. Drug

    Artenimol

    go.drugbank.com/drugs/DB11638
    ApprovedInvestigational

    Artenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated Plasmodium falciparum infections [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2011 in com...

    Mixtures: D-ARTEPP, D-ARTEPP DISPERSIBLECategories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2D6 Inhibitors
  9. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    [A253917] Prior to its FDA approval, dimethyl fumarate had been used in Germany for treatment of psoriasis.[A253917] … It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: YARDIX® 240MG, TECFIDERA® 240MG
  10. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: 5-Carbamoyl-5H-dibenz(b,f)azepine, 5-carbamoyl-5H-dibenz[b,f]azepine