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Displaying results 1421 - 1430 of 2828 in total
  1. Drug

    Leptazoline D

    go.drugbank.com/drugs/DB15554
    Experimental

    Also see [Leptazoline A], [Leptazoline B], and [Leptazoline C].

  2. Drug

    CSIC002

    go.drugbank.com/drugs/DB18584
    Experimental

    CSIC002 is a small-molecule Sema-3A inhibitor. It is being investigated for the treatment of anterior ischemic optic neuropathy.

  3. Target

    Tubulin gamma-1 chain

    go.drugbank.com/bio_entities/BE0003713
    TargetHumans

    Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed:38305685, PubMed:38609661, PubMed:39321809).

    Synonyms: Gamma-tubulin complex component 1
  4. Drug

    AV608

    go.drugbank.com/drugs/DB05072
    Investigational

    AV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).

  5. Target

    Sodium/myo-inositol cotransporter 2

    go.drugbank.com/bio_entities/BE0017647
    TransporterHumans

    Exclusively responsible for apical MI transport and absorption in intestine (By similarity). Can also transport D-chiro-inositol (DCI) but not L-fucose (PubMed:15172003, PubMed:19032932).

    Synonyms: Sodium/myo-inositol transporter 2
  6. Drug

    Azoxystrobin

    go.drugbank.com/drugs/DB07401
    Experimental

    Azoxystrobin is a methoxyacrylate analog and a strobilurin fungicide.

    Categories: Electron Transport Complex III
  7. Drug

    WZB-117

    go.drugbank.com/drugs/DB16764
    Experimental

    Categories: Glucose Transporter Type 1, antagonists & inhibitors
  8. Drug

    Fenpyroximate

    go.drugbank.com/drugs/DB16164
    Investigational

    Fenpyroximate is under investigation in clinical trial NCT02533336 (The Effectiveness of Non-pyrethroid Insecticide-treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania).

    Categories: Electron Transport Complex I, antagonists & inhibitors
  9. Drug

    Poliglusam

    go.drugbank.com/drugs/DB11234
    ApprovedInvestigational

    In comparison, commercial poliglusam is derived from deacetylation of chitin contained in the shells of various sea crustaceans such as shrimps [L999].

  10. Target

    Hepatic sodium/bile acid cotransporter

    go.drugbank.com/bio_entities/BE0003644
    TransporterTargetHumans

    Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic … As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary

    Synonyms: Na(+)/taurocholate transport proteinFunction: bile acid transmembrane transporter activity