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Displaying results 1421 - 1430 of 2744 in total
  1. Drug

    Norgesterone

    go.drugbank.com/drugs/DB21409
    Experimental

    The usage of the INN stem '-terone' in the name indicates that Norgesterone is a antiandrogen. Norgesterone has a monoisotopic molecular weight of 300.21 Da.

  2. Drug

    Pitenodil

    go.drugbank.com/drugs/DB21442
    Experimental

    The usage of the INN stem '-dil' in the name indicates that Pitenodil is a vasodilator. Pitenodil has a monoisotopic molecular weight of 353.18 Da.

  3. Drug

    Haloprogesterone

    go.drugbank.com/drugs/DB20259
    Experimental

    The usage of the INN stem '-terone' in the name indicates that Haloprogesterone is a antiandrogen. Haloprogesterone has a monoisotopic molecular weight of 410.13 Da.

  4. Target

    Nuclear factor of activated T-cells, cytoplasmic 1

    go.drugbank.com/bio_entities/BE0004878
    TargetHumans

    Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation a...

    Synonyms: NFAT transcription complex cytosolic component
  5. Drug

    MB-107

    go.drugbank.com/drugs/DB18566
    Experimental

    MB-107 consists of mobilized peripheral blood-derived autologous CD34+ hematopoietic stem cells that are genetically modified to express the IL2RG gene.

  6. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

    go.drugbank.com/bio_entities/BE0000191
    TargetEnzymeHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor … Essential for the catalytic activity and assembly of complex I (PubMed:14729820, PubMed:24028823, PubMed:30140060)

    Synonyms: Complex I-30kD
  7. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

    go.drugbank.com/bio_entities/BE0000729
    TargetEnzymeHumans

    Essential for the catalytic activity of complex I (PubMed:22036843, PubMed:30922174). Essential for the assembly of complex I (By similarity). … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-49kD
  8. Target

    Protein SLC31A2

    go.drugbank.com/bio_entities/BE0003662
    TransporterHumans

    export and modulates the copper and cisplatin accumulation via SLC31A1 (By similarity) … Does not function as a copper(1+) importer in vivo (By similarity). However, in vitro functions as a low-affinity copper(1+) importer (PubMed:17617060, PubMed:17944601).

    Synonyms: Copper transporter 2Function: copper ion transmembrane transporter activity
  9. Drug

    Tenofovir alafenamide

    go.drugbank.com/drugs/DB09299
    ApprovedInvestigational

    Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil].

    Categories: Vitamin B Complex
  10. Drug

    Ethoxzolamide

    go.drugbank.com/drugs/DB00311
    ApprovedWithdrawn

    Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confe...

    Categories: Genito Urinary System and Sex Hormones