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Defibrotide
go.drugbank.com/drugs/DB04932ApprovedInvestigationalIt is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. In the USA it is was approved in March, 2016 as Defitelio. … It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects).
Droperidol
go.drugbank.com/drugs/DB00450ApprovedInvestigationalVet approvedIt is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593) … It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the
Products: Xomolix 2,5 mg/ml Injektionslösung, PONVeridol 1,25 mg/ml InjektionslösungOlsalazine
go.drugbank.com/drugs/DB01250Approved[A257063] It was first developed for delivering mesalamine to the colon without the use of [sulfapyridine]. … [A257078] Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.
Tegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnmechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and … in female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population.
Thyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is inconsistent with the stated strength of the tablet. … [A190813] Thyroid extracts were never FDA approved as their use in the United States predates the FDA.[A190831]
Coagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric patients with congenital factor IX deficiency (Hemophilia B).
Elbasvir
go.drugbank.com/drugs/DB11574Approved[A19593] Substitutions at amino acid positions 28, 30, 31, or 93 are known to confer resistance to elbasvir. … Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 with or without [ribavirin] depending on the presence of resistance-associated amino acid substitutions
Mixtures: ZEPATIER 50 MG/100 MG FİLM KAPLI TABLET, 28 ADETCurcuma xanthorrhiza oil
go.drugbank.com/drugs/DB11265ApprovedNutraceuticalIt has been used in the treatment of stomach diseases, liver disorders, constipation, bloody diarrhoea, dysentery, children’s fevers, hypotriglyceridaemic, haemorrhoids and skin eruptions [A33162]. … _Curcuma xanthorrhiza_ oil is found as an active ingredient in cosmetic and hygienic products, and marketing of products containing _Curcuma xanthorrhiza_ oil is authorized in some European countries including
Hesperidin
go.drugbank.com/drugs/DB04703ApprovedInvestigationalHesperidin is a flavan-on glycoside found in citrus fruits.
Mixtures: DAFLON-SET, Hemo Rid CT TabletBedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigational[A261856] Currently, bedaquiline is the last-line anti-TB drug and must only be used in an appropriate combination regimen.[L48506,A261866] … [A261856,A261861] It is the first drug that was approved in the last 40 years by the FDA for TB unresponsive to current treatments on the market.
Products: SIRTURO 100 MG, SIRTURO 100 MG TABLET, 24 ADET