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Padeliporfin
go.drugbank.com/drugs/DB15575ApprovedInvestigational[A244699] Padeliporfin was first approved by the European Commission on November 10, 2017, for the treatment of low-risk prostate cancer in adults meeting certain clinical criteria.[L39799]
Categories: Sensitizers Used in Photodynamic/radiation TherapyStress Incontinence (Female) (Male)
go.drugbank.com/conditions/DBCOND0128715Drugs: DuloxetineSynonyms: SI - Stress incontinence, Urinary Stress Incontinence (SI)Misoprostol
go.drugbank.com/drugs/DB00929ApprovedInvestigational[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the … [A181586] Misoprostol was granted FDA approval on 27 December 1988.[L7616]
Categories: Prostaglandin E1 Analog, Prostaglandins E, SyntheticIvacaftor
go.drugbank.com/drugs/DB08820ApprovedInvestigational, an ion channel involved in the transport of chloride and sodium ions across cell membranes. … It was approved by the Food and Drug Administration on January 31, 2012[L768], and by Health Canada in late 2012.
Synonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamideEdetic acid
go.drugbank.com/drugs/DB00974ApprovedInvestigationalVet approvedIt is used in pharmaceutical manufacturing and as a food additive.
Synonyms: N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)Categories: Compounds used in a research, industrial, or household settingTroglitazone
go.drugbank.com/drugs/DB00197ApprovedWithdrawnTroglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by [pioglitazone] and [rosiglitazone].
Categories: Drugs Used in DiabetesThrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalMedical thrombin is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. … Failure to clot blood occurs in the rare case where the primary clotting defect is the absence of fibrinogen itself.
Mixtures: SAN. VE TİC. LTD.Peginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnPeginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed ...
Categories: Compounds used in a research, industrial, or household settingCalcium polycarbophil
go.drugbank.com/drugs/DB14684ApprovedLess gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. … Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion.
Categories: Compounds used in a research, industrial, or household settingProducts: Fiber-ON-tabletDimethicone 410
go.drugbank.com/drugs/DB14005Approved[L1769] It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%. … Dimethicone is a silicone-based polymer used as a moisturizer in different skin OTC products.[A32462] It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit.