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Displaying results 1441 - 1450 of 5897 in total
  1. Drug

    Chymopapain

    go.drugbank.com/drugs/DB06752
    ApprovedWithdrawn

    Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest. … [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity.[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982.

  2. Drug

    Kappadione

    go.drugbank.com/drugs/DB09332
    Approved

    It has been found to have carcinogenic potential in mammalian cells as well as cytotoxic properties [L1544]. … Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is

  3. Drug

    Fibrinolysin

    go.drugbank.com/drugs/DB05254
    Investigational

    Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond.

  4. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    [T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain.

    Mixtures: Co-gesicCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Dalteparin

    go.drugbank.com/drugs/DB06779
    ApprovedInvestigational

    Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.

    Products: FRAGMIN 5000IE P FO FER SI, FRAGMIN P FO 5000IE FER+SI
  6. Drug

    Pancrelipase amylase

    go.drugbank.com/drugs/DB11065
    ApprovedInvestigational

    [T177] The pancrelipase amylase is a single polypeptide chain containing two SH groups and four disulfide bridges.

  7. Drug

    Attapulgite

    go.drugbank.com/drugs/DB01574
    ApprovedVet approvedWithdrawn

    Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications.

  8. Drug

    Salsalate

    go.drugbank.com/drugs/DB01399
    ApprovedInvestigational

    In contrast to aspirin, salsalate causes no greater fecal gastrointestinal blood loss than placebo. … Salsalate is readily soluble in the small intestine where it is partially hydrolyzed to two molecules of salicylic acid.

    Synonyms: o-Salicylsalicylic acid, O-Salicylcylsalicylsäure
  9. Drug

    Carbenicillin

    go.drugbank.com/drugs/DB00578
    Approved

    It is susceptible to gastric juice and penicillinase and may damage platelet function.

  10. Drug

    Ubrogepant

    go.drugbank.com/drugs/DB15328
    ApprovedInvestigational

    to its predecessors. … [A189195] They appear to be better tolerated, do not contribute to medication overuse headaches, and carry no apparent cardiovascular risk, making them suitable for use in patients with cardiovascular